Cheonggukjang, a soybean paste fermented with B-licheniformis-67 prevents weight gain and improves glycemic control in high fat diet induced obese mice
Cheonggukjang, a soybean paste fermented with B-licheniformis-67 prevents weight gain and improves glycemic control in high fat diet induced obese mice
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DOI：
10.3164/jcbn.15-30
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发表时间：
2016-07-01
影响因子：
2.4
通讯作者：
Cha, Youn-Soo
中科院分区：
文献类型：
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作者：
Choi, Joo-Hee;Pichiah, P. B. Tirupathi;Cha, Youn-Soo
在这项研究中，我们研究了大豆酱清谷酱，发酵与聚γ-谷氨酸生产地衣芽孢杆菌-67在饮食诱导肥胖的C57 BL/6 J小鼠的减肥效果。将40只4周龄雄性C57 BL/6 J小鼠分为4个饮食组：正常饮食对照组、高脂饮食对照组、含30%未发酵大豆的高脂饮食组和含30%经地衣芽孢杆菌-67发酵的清谷姜的高脂饮食组。饮食干预13周后，处死小鼠;检查血清和组织样品。血清和肝脏脂质谱、血糖、胰岛素、瘦素水平较低（
In this study, we investigated the anti-obesity effects of soybean paste Cheonggukjang, fermented with poly gamma glutamic acid producing Bacillus licheniformis-67 in diet induced obese C57BL/6J mice. Forty male C57BL/6J mice aged 4 weeks were divided into four dietary groups; normal diet control, high fat diet control, high fat diet containing 30% of unfermented soybean and high fat diet containing 30% Cheonggukjang fermented with Bacillus licheniformis-67. After 13 weeks of dietary intervention the mice were sacrificed; serum and tissue samples were examined. Serum and hepatic lipid profile, blood glucose, insulin, leptin level were lower (