Antibody testing in Lyme disease. A comparison of results in four laboratories.
Antibody testing in Lyme disease. A comparison of results in four laboratories.
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莱姆病的抗体检测。
DOI：
10.1001/jama.1989.03430240067031
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
S. I. Shahied
中科院分区：
文献类型：
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作者：
Brian S. Schwartz;Michael D. Goldstein;José M. C. Ribeiro;Terry L. Schulze;S. I. Shahied
为了评估实验室间和实验室内在莱姆病血清学检测方面的一致性，我们将新泽西州132名户外工作人员的血清样本送到了多达四个独立的实验室。其中包括一个州卫生部实验室、一个大型商业实验室和两个研究实验室。所采用的一致性度量，即卡帕统计，在四个实验室中的范围从.45到.53，在商业实验室中从.50到.54。这些值代表低水平的一致性。这些数据表明，莱姆病血清学检测程序应该标准化，以便莱姆病检测结果在实验室之间更具可比性。
To evaluate the interlaboratory and intralaboratory agreement in the performance of Lyme disease serological testing, we sent serum specimens from 132 outdoor workers in New Jersey to as many as four independent laboratories. These included one state department of health laboratory, one large commercial laboratory, and two research laboratories. The measurement of agreement employed, the kappa statistic, ranged from .45 to .53 among the four laboratories and from .50 to .54 within the commercial laboratory. These values represent low levels of agreement. The data suggest that Lyme disease serological testing procedures should be standardized so that Lyme disease test results are more comparable between laboratories.