PARASAGITTAL ZONATION WITHIN OLIVOCEREBELLAR PROJECTION .1. CLIMBING FIBER DISTRIBUTION IN VERMIS OF CAT CEREBELLUM
PARASAGITTAL ZONATION WITHIN OLIVOCEREBELLAR PROJECTION .1. CLIMBING FIBER DISTRIBUTION IN VERMIS OF CAT CEREBELLUM
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DOI：
10.1002/cne.901740304
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发表时间：
1977-01-01
影响因子：
2.5
通讯作者：
VOOGD, J
中科院分区：
文献类型：
--
作者：
GROENEWEGEN, HJ;VOOGD, J
After lesions of inferior olive, survival times of 5-12 days and Nauta staining, degeneration was present in white matter and central cerebellar nuclei and Deiters'' nucleus. Shorter survival times from 40-60 h and Fink-Heimer impregnation revealed degenerating climbing fiber terminals in the molecular layer. With 3H-leucine autoradiography and survival times of 3-7 days the climbing fibers could be traced. Olivocerebellar fibers cross in the brain stem and terminate contralaterally in cortex and central nuclei. Occasional labeling of mossy fiber terminals was explained by involvement of reticular nuclei. Small parts of the inferior olive connect with narrow longitudinal zones in the cortex through compartments in the white matter. The corresponding distribution of olivocerebellar fibers and Purkinje cell axons over these compartments suggested that the organization of the olivocerebellar and corticonuclear projection is essentially similar. Collaterals always terminate in the central cerebellar nucleus which receives a corticonuclear projection from the zone in which the parent fibers terminate. Caudal medial accessory olive projects to medial vermal zone A and to fastigial nucleus, subnucleus .beta. projecting to lobule VII and caudal fastigial nucleus. Caudal dorsal accessory olive projects to lateral vermal zone B in lobules I-VI, Deiters'' nucleus and dorsomedial subnucleus of interposed nucleus. The caudal principal olive (dorsal cap, ventrolateral outgrowth receiving visual and vestibular input) projects to flocculo-nodular lobe.
