Recurrent ventricular fibrillation and modes of death in survivors of out-of-hospital ventricular fibrillation.
Recurrent ventricular fibrillation and modes of death in survivors of out-of-hospital ventricular fibrillation.
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院外心室颤动幸存者的复发性心室颤动和死亡模式。
DOI：
10.1056/nejm197508072930601
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
L. Cobb
中科院分区：
文献类型：
--
作者：
W. Schaffer;L. Cobb
我们研究了院外心室颤动复苏患者的死亡原因。51个月内，234例患者成功复苏、住院并出院。在随访观察期间，89例复发性心室颤动或死亡（或两者兼有）发生，其中64例（72%）是意外的院外循环骤停。在观察心电图的44次发作中，心室颤动发生率为77%。10例患者一次或多次复发性心室颤动存活。再发循环骤停的中位时间为前一次发作后20周。前驱症状不常见，在心脏骤停时活动水平一般较低。猝死（或两者兼而有之）的反复心室颤动主要发生在初始发作与急性心肌梗死无关的情况下。从心室颤动中复苏的患者容易早期复发，可能反映了持续的心肌电不稳定。
We examined the causes of death in patients previously resuscitated from out-of-hospital ventricular fibrillation. In 51 months, 234 patients were sucessfully resuscitated, hospitalized and discharged home. During follow-up observation, 89 episodes of recurrent ventricular fibrillation or death (or both) occurred, 64 of which (72 per cent) were unexpected, out-of-hospital circulatory arrests. Ventricular fibrillation occurred in 77 per cent of the 44 episodes in which the electrocardiogram was observed. Ten patients survived one or more episodes of recurrent ventricular fibrillation. Median time to recurrent ciruclatory arrest was 20 weeks after the preceding episode. Prodromal symptoms were infrequent, and activity levels were generally low at the time of cardiac arrest. Recurrent ventricular fibrillation of sudden death (or both) occurred predominantly when the initial episode was not associated with acute myocardial infarction. Patients resuscitated from ventricular fibrillation are susceptible to early recurrence, probably reflecting continuing myocardial electrical instability.