Neural correlates of eye-gaze detection in young children with autism
Neural correlates of eye-gaze detection in young children with autism
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DOI：
10.1016/s0010-9452(08)70271-5
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发表时间：
2005-06-01
期刊：
影响因子：
3.6
通讯作者：
Johnson, MH
中科院分区：
文献类型：
--
作者：
Grice, SJ;Halit, H;Johnson, MH
各种报告表明，年龄较大的自闭症儿童和成人在进行眼睛注视处理方面存在困难。然而，人们对这种困难的神经或发育起源知之甚少。在本研究中，我们使用高密度事件相关电位（HD-ERP）来记录自闭症幼儿及其年龄匹配对照的凝视处理的神经相关性。此外，为了确定正常的凝视处理发育，我们还测试了非自闭症成人组。从自闭症儿童身上获得的数据与之前在典型 4 个月大婴儿中观察到的数据相似。相反，对照组表现出与典型成年人相同的模式。这些发现表明，自闭症幼儿的注视方向处理的神经相关性可能会延迟。
Various reports have demonstrated difficulties in eye-gaze processing in older children and adults with autism. However, little is known about the neural or developmental origin of such difficulties. In the present study, we used high-density Event-Related Potentials (HD-ERPs) to record the neural correlates of gaze processing in young children with autism, and their age-matched controls. In addition, to determine normal gaze processing development we also tested a non-autism adult group. The data obtained from the children with autism resembled that previously observed in typical 4-month old infants. In contrast, the control group showed the same pattern as typical adults. These findings suggest that the neural correlates of gaze direction processing may be delayed in young children with autism.