Parkinsonian signs and functional disability in old age
Parkinsonian signs and functional disability in old age
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DOI：
10.1080/03610730601006370
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发表时间：
2007-01-01
影响因子：
1.8
通讯作者：
Bennett, David A.
中科院分区：
文献类型：
--
作者：
Fleischman, Debra A.;Wilson, Robert S.;Bennett, David A.
关于帕金森症状和功能障碍之间的联系知之甚少。作者研究了四种帕金森症状（步态，僵硬，运动迟缓，震颤）与日常生活中进行身体和工具活动的能力之间的关系，在一个大型的老年拉什记忆和衰老项目参与者队列中，他们没有痴呆症，帕金森病和抗精神病药物使用。在一系列逻辑回归方程，控制年龄，性别，教育，抑郁症状，认知能力，慢性疾病，精神药物的使用，更高水平的帕金森症状与更高水平的残疾在执行日常生活的身体和工具活动。
Little is known about the association between parkinsonian signs and functional disability. The authors examined the associations between four parkinsonian signs (gait, rigidity, bradykinesia, tremor) and the ability to perform physical and instrumental activities of daily living, in a large cohort of older Rush Memory and Aging Project participants who were free of dementia, Parkinson's disease, and antipsychotic drug use. In a series of logistic regression equations that controlled for age, sex, education, depressive symptoms, cognitive ability, chronic medical conditions, and psychotropic drug use, higher levels of parkinsonian signs were associated with higher levels of disability in performing both physical and instrumental activities of daily living.