Response to dynamic exercise of the orthotopically transplanted human heart in men immunosuppressed with cyclosporine.
Response to dynamic exercise of the orthotopically transplanted human heart in men immunosuppressed with cyclosporine.
复制标题
环孢菌素免疫抑制男性对原位移植人心脏动态运动的反应。
DOI：
10.1016/0002-9149(89)90547-x
复制
发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Hess,ML
中科院分区：
文献类型：
--
作者：
Nixon,JV;Rosenburg,H;Romhilt,D;Thompson,JA;Hastillo,A;Hess,ML
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Experimental and human studies of the orthotopically transplanted human heart have shown that, at rest, the denervated heart is characterized by a high resting heart rate and a diminished chronotropic reserve.1−5Human studies have been carried out in relatively small numbers of patients before the more recent advances in immunosuppressive therapy and the increasingly sophisticated management of the patient who has had transplantation. We quantified the hemodynamic response to graded treadmill exercise in stable patients who continue their contemporary immunosuppressive therapy including cyclosporine, and undergo stress testing within 12 months of their successful orthotopic cardiac transplantation.