Association between a brief alcohol craving measure and drinking in the following week
Association between a brief alcohol craving measure and drinking in the following week
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DOI：
10.1111/add.13311
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发表时间：
2016-06-01
期刊：
影响因子：
6
通讯作者：
Weiss, Roger D.
中科院分区：
文献类型：
--
作者：
McHugh, R. Kathryn;Fitzmaurice, Garrett M.;Weiss, Roger D.
背景和目的酒精渴求被认为是酒精使用的预测指标，特别是在不久的将来。在临床实践中对渴望的评估需要简明、简单的措施，这些措施可以常规实施。这项研究测试了更大的酒精渴望是否与随后一周饮酒的可能性更高有关。设计：联合研究(结合酒精依赖的药物治疗和行为干预)是一项治疗酒精依赖的大型、多点临床试验。参与者被随机(按地点分层)到九种治疗条件中的一种，包括药物治疗和心理治疗的组合。在整个治疗期间，每隔一周评估一次渴望。在全美11个学术场所设置药物使用障碍治疗环境。参与者将研究中的参与者(n=1370)与可用的渴望数据结合在一起。用三个条目的渴求自评量表测量渴求。饮酒使用时间线回馈方法进行评估，并定义为在每个研究周饮酒。研究结果平均每个参与者有5.8个观察对(可能有7个)。在接下来的一周内，渴求与饮酒密切相关[B=0.2 7，标准差=0.0 6，Wald chi(2)=43.34，OR=1.3 1，95%可信区间=1.16，1.47，P<；0.001]。渴望程度每增加1个单位，在接下来的一周饮酒的可能性就会增加31%。结论在接下来的一周里，饮酒欲望与饮酒密切相关。临床医生可以使用简短的自我报告渴望量表来有效地测量酒精渴望。
Background and Aims Craving for alcohol is thought to be a predictor of alcohol use, particularly in the near future. The assessment of craving in clinical practice requires brief, simple measures that can be implemented routinely. This study tested whether greater alcohol craving was associated with a higher likelihood of alcohol use in the subsequent week. Design The COMBINE Study (Combining Medications and Behavioral Interventions for Alcohol Dependence) was a large, multi-site clinical trial of treatment for alcohol dependence. Participants were randomized (stratified by site) to one of nine treatment conditions involving combinations of pharmacotherapy and psychotherapy. Craving was assessed every other week throughout the treatment period. Setting Substance use disorder treatment settings at 11 academic sites across the United States. Participants Participants from the COMBINE Study (n = 1370) with available craving data. Measurements Craving was assessed using the three-item self-report Craving Scale. Drinking was assessed using the Timeline Followback method, and was defined as alcohol use in each study week. Findings There was an average of 5.8 (of a possible seven) observation pairs per participant. Craving was associated strongly with alcohol use in the following week [B = 0.27, standard error (SEB) = 0.06, Wald chi(2) = 43.34, odds ratio (OR) = 1.31, 95% confidence interval (CI) = 1.16, 1.47, P < 0.001]. For each 1-unit increase in the Craving Scale, the likelihood of drinking in the next week was 31% higher. Conclusions Craving for alcohol is associated strongly with alcohol use in the following week. Clinicians can measure alcohol craving effectively using a brief self-report craving scale.