Fear of Cancer Recurrence and Death Anxiety: Unaddressed Concerns for Adult Neuro-oncology Patients
Fear of Cancer Recurrence and Death Anxiety: Unaddressed Concerns for Adult Neuro-oncology Patients
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DOI：
10.1007/s10880-019-09690-8
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发表时间：
2019-12-17
影响因子：
2.2
通讯作者：
Braun, Sarah
中科院分区：
文献类型：
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作者：
Loughan, Ashlee R.;Lanoye, Autumn;Braun, Sarah
原发性脑肿瘤（PBT）患者可能会经历生存困扰；然而，很少有研究探讨这个问题。本研究的目的是（1）系统回顾心理肿瘤学文献中有关与进展、复发和死亡相关的恐惧/焦虑的 PBT 表现，以及（2）初步评估 PBT 患者样本中对死亡的恐惧的患病率。对三个数据库的系统检索产生了 1555 篇文章供审查。其中，327 项研究符合纳入标准（患者样本 N = 132,951）。只有八项研究（占参与者的 0.18%）纳入了 PBT 诊断的患者，这可能是由于认知障碍或特定治疗参数等排除标准可能会禁止 PBT 患者参与。对八项纳入研究的结果的审查揭示了混合方法和有限的人口统计分析；存在痛苦与抑郁和焦虑加剧以及整体生活质量恶化相关。从原始数据收集来看，大约三分之一的 PBT 患者认可对死亡的恐惧，这与抑郁症的严重程度呈正相关。总而言之，结果表明 PBT 患者在存在主义心理肿瘤学文献中的代表性严重不足，尽管初步结果表明这些担忧普遍存在。未来对神经肿瘤学中存在的痛苦的研究是有必要的。
Primary brain tumor (PBT) patients may experience existential distress; however, few studies have examined this issue. The objectives of this study were to (1) systematically review PBT representation in psycho-oncology literature regarding fear/anxiety related to progression, recurrence, and death and (2) preliminarily assess the prevalence of fear of dying in a sample of PBT patients. Systematic searching of three databases yielded 1555 articles for review. Of these, 327 studies met inclusion criteria (patient sampleN = 132,951). Only eight studies (0.18% of the participants) included patients with a PBT diagnosis, potentially due to exclusion criteria such as cognitive impairment or specific treatment parameters which may prohibit PBT patient participation. Review of the results from the eight included studies revealed mixed methods and limited demographic analyses; existential distress was correlated with heightened depression and anxiety, and overall worsened quality of life. From the original data collection, approximately one-third of PBT patients endorsed fear of dying, which was positively related to depression severity. Taken together, results suggest that PBT patients are considerably underrepresented in existential psycho-oncology literature, despite preliminary findings suggesting prevalence of these concerns. Future research on existential distress in neuro-oncology is warranted.