In perspective: the patient at the heart of research in acute cardiovascular care.
In perspective: the patient at the heart of research in acute cardiovascular care.
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透视：患者是急性心血管护理研究的核心。
DOI：
10.1093/ehjacc/zuad027
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Thomson RJ
中科院分区：
文献类型：
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作者：
Thomson RJ
患者和公众参与是研究设计的基本组成部分，研究资助者和监管机构越来越要求患者和公众参与。除了有利于其的道德和伦理论据外，它还具有改善研究的可及性和透明度以及优化研究招募和保留的潜力。虽然急性心血管护理的临床试验传统上集中在“硬”结果上，如死亡率或主要不良心血管事件，但越来越多的人认识到，这些试验未能全面反映患者的经验。以患者为中心的结果旨在衡量对患者更有价值的事情，使用经过验证的工具来量化症状，患者自我报告或新的结果，如住院和住院天数。本书探讨了患者和公众参与背后的基本原理，以及支持使用以患者为中心的结果的背景和证据，并讨论了潜在的挑战以及如何减轻这些挑战。
Patient and public involvement is a fundamental part of research design and is increasingly required by research funders and regulators. In addition to the moral and ethical arguments in its favour, it has the potential to improve the accessibility and transparency of research and to optimize study recruitment and retention. Whilst clinical trials in acute cardiovascular care have traditionally focussed on ‘hard’ outcomes, such as mortality or major adverse cardiovascular events, there is increasing recognition that these fail to capture the full breadth of patient experience. Patient-centred outcomes aim to measure things of greater value to patients, using validated tools to quantify symptoms, patient self-reports, or novel outcomes such as days alive and outside hospital. ThisIn Perspectivecommentary explores the rationale behind patient and public involvement and the background to and evidence supporting the use of patient-centred outcomes and discusses potential challenges and how they can be mitigated.