Row formation and other types of arrangement of cartilage cells in endochondral ossification
Row formation and other types of arrangement of cartilage cells in endochondral ossification
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DOI：
10.1002/ar.1090460409
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发表时间：
1930-09-01
影响因子：
--
通讯作者：
Dodds, GS
中科院分区：
文献类型：
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作者：
Dodds, GS
在狗、猫、猪和人的胎儿和幼年动物中研究了成排的过程。软骨细胞的成排是由成排母细胞连续分裂形成的，其中第一次分裂产生2个扁平细胞。这些成对的细胞通过反复分裂产生不同长度的细胞。细胞保持扁平，排列得像一堆堆硬币，直到排满细胞，然后它们大大扩大，为侵入骨髓做准备。在这个过程中，细胞没有重新排列。在行中扁平细胞的分裂中，每个细胞通过有丝分裂产生2个半圆形细胞，每个半圆形细胞通过楔形延伸超过其同伴而恢复盘状形状。在某些情况下，不会形成行，但会将单元格分组到单元格嵌套中。在每个骨的原始中心的开始，没有特殊的分组，细胞均匀分布，因此它们的扩大产生薄小梁的网络。
The process of row formation was studied in fetuses and young animals of dog, cat, pig, and man. Rows of cartilage cells form by successive divisions of row-mother cells, the first division of which produces 2 flattened cells. Rows of various lengths are produced from these pairs of cells by repeated divisions. The cells remain flat and arranged like piles of coins until the full number of cells in the rows are attained, after which they enlarge greatly, preparatory for the invasion of the marrow. There is no rearrangement of cells during this process. In the divisions of the flattened cells in the rows, each cell gives rise by mitosis to 2 semicircular cells, each of which resumes the discoid form by growth of a wedge-shaped extension past its fellow. In certain situations rows do not form, but the cells are grouped instead in cell nests. In the beginning of the primary center of each bone there is no special grouping, the cells being uniformly distributed, so that their enlargement produces a network of thin trabeculae.