The role of psychiatric disorders in predicting drug dependence treatment outcomes
The role of psychiatric disorders in predicting drug dependence treatment outcomes
复制标题
DOI：
10.1176/appi.ajp.160.5.890
复制
发表时间：
2003-05-01
影响因子：
17.7
通讯作者：
Spitznagel, EL
中科院分区：
文献类型：
--
作者：
Compton, WM;Cottler, LB;Spitznagel, EL
目的：以前的研究表明，精神疾病在滥用酒精和药物的人中很常见，但很少有研究探讨精神疾病与药物治疗结果的关系。作者进行了这样一个examination.Method：他们成功地重新采访了401药物依赖的主题（94%的基线治疗样本），并确定他们的药物滥用状态在后续12个月后。结果：分析表明，几个基线精神疾病预测更糟糕的结果在后续。重度抑郁症预测使用更多的物质，并有更多的药物依赖诊断和症状。酒精依赖预测更多的依赖诊断，反社会人格障碍预测使用大量的物质，广泛性焦虑症预测有更多的依赖诊断。男性之间的结果与精神状态比女性之间的结果更密切相关，除了恐惧症，预测更好的结果在women.Conclusions：这些结果是独特的，在他们的评估个人依赖于非法物质。总的来说，作者发现患有恐惧症的女性有更好的结果，而患有精神疾病的男性，患有重度抑郁症的男性和患有反社会人格障碍的男性的结果更差。
Objective: Previous research has demonstrated that psychiatric disorders are common among people who abuse alcohol and drugs, but few studies have examined the relationship of psychiatric disorders to drug treatment outcome. The authors conducted such an examination.Method: They successfully reinterviewed 401 drug-dependent subjects (94% of the baseline in-treatment sample) and determined their drug abuse status at follow-up 12 months later.Results: Analyses indicated that several baseline psychiatric disorders predicted worse outcomes at follow-up. Major depression predicted using a larger number of substances and having more drug dependence diagnoses and symptoms. Alcohol dependence predicted more dependence diagnoses, antisocial personality disorder predicted using a larger number of substances, and generalized anxiety disorder predicted having more dependence diagnoses. Outcomes among men were more closely associated with psychiatric status than outcomes among women, except for phobias, which predicted a better outcome among women.Conclusions: These results are unique in their assessment of individuals dependent on illicit substances. Overall, the authors found that women with phobias had better outcomes and that men with psychiatric disorders in general, men with major depression, and men with antisocial personality disorder had worse outcomes.