Skin Testing for Tuberculosis
Skin Testing for Tuberculosis
复制标题
结核病皮肤测试
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
C. Dacso
中科院分区：
文献类型：
--
作者：
C. Dacso
结核病的皮肤测试（TB）使用一种形式的诊断试剂结核菌素。多次穿刺技术被称为Heaf或tine试验，而纯化蛋白衍生物（PPD-S）通常通过皮内注射施用，以Charles Mantoux的名字被称为Mantoux技术，Charles Mantoux在20世纪早期描述了该技术。旧的阿曲库林在临床上仅用于多穿刺技术。PPD-S也可用于某些系统的多次穿刺，但标准PPD-S溶液不得用于多次穿刺技术，因为其浓度未针对该技术进行标准化。在多穿刺系统中，只能使用为该系统设计的PPD-S。PPD-S偶尔以“第一强度”（1 TU）或“第二强度”（250 TU）给药，相当于1：100浓度的OT。第一和第二强度结核菌素的临床效用尚不明确。中等强度的PPD-S仍然是研究得最好的。PPD-S，即使用吐温-80稳定，对光敏感，在一定程度上对温度敏感。因此，它应该储存在冰箱里。
Skin testing for tuberculosis (TB) utilizes a form of the diagnostic reagent tuberculin . The multiple puncture technique is referred to as the Heaf, or tine test, whereas purified protein derivative (PPD-S) is commonly administered by intradermal injection, called the Mantoux technique after Charles Mantoux, who described the technique in the early part of the twentieth century . Old Tuberculin is used clinically only in the multiple puncture technique. PPD-S can also be used in some systems for multiple puncture, but the standard PPD-S solution should never be used in the multiple puncture technique as its concentration is not standardized for the technique . In the multiple puncture systems, only PPD-S designed for that system should be used . PPD-S occasionally is administered as "first strength" (1 TU) or "second strength" (250 TU) and is equivalent to a 1 :100 concentration of OT . The clinical utility of firstand secondstrength tuberculin is poorly defined . Intermediate-strength PPD-S remains the best studied . PPD-S, even when stabilized with Tween-80, is sensitive to light and to a certain extent to temperature . Thus it should be stored in a refrigerator .
影响因子：
158.5
作者：
SELWYN, PA;HARTEL, D;FRIEDLAND, GH
通讯作者：
FRIEDLAND, GH