Enhancement of hidden structures of early skin fibrosis using polarization degree patterns and Pearson correlation analysis.
Enhancement of hidden structures of early skin fibrosis using polarization degree patterns and Pearson correlation analysis.
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使用偏振度模式和皮尔逊相关分析增强早期皮肤纤维化的隐藏结构。
DOI：
10.1117/1.2073727
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发表时间：
2005
影响因子：
3.5
通讯作者：
Gandjbakhche,Amir
中科院分区：
文献类型：
--
作者：
Sviridov,AlexanderP;Chernomordik,Victor;Hassan,Moinuddin;Boccara,AlbertC;Russo,Angelo;Smith,Paul;Gandjbakhche,Amir
用单剂量的 X 射线照射无胸腺裸鼠的皮肤，引发纤维化。通过用线性偏振探测光照射小鼠皮肤来拍摄受照射小鼠的数码照片。偏振度表面分布的特定模式能够检测视觉上不明显的初始皮肤纤维化结构。基于高频噪声的傅立叶滤波的偏振度的原始空间分布的数据处理改善了图像中所揭示结构的主观感知。此外，皮尔逊相关分析提供了有关皮肤结构尺寸和方向性的信息。
The skin of athymic nude mice is irradiated with a single dose of x-ray irradiation that initiated fibrosis. Digital photographs of the irradiated mice are taken by illuminating the mouse skin with linearly polarized probe light of. The specific pattern of the surface distribution of the degree of polarization enables the detection of initial skin fibrosis structures that were not visually apparent. Data processing of the raw spatial distributions of the degree of polarization based on Fourier filtering of the high-frequency noise improves subjective perception of the revealed structure in the images. In addition, Pearson correlation analysis provides information about skin structural size and directionality.