A Population-Based Study of the Prevalence of Abnormal Uterine Bleeding and its Related Factors among Iranian Reproductive-Age Women: An Updated Data.
A Population-Based Study of the Prevalence of Abnormal Uterine Bleeding and its Related Factors among Iranian Reproductive-Age Women: An Updated Data.
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关于伊朗育龄妇女异常子宫出血及其相关因素的人群研究：最新数据。
DOI：
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发表时间：
2017
影响因子：
2.1
通讯作者：
F. Azizi
中科院分区：
文献类型：
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作者：
Hadigheh Kazemijaliseh;F. Ramezani Tehrani;S. Behboudi;D. Khalili;F. Hosseinpanah;F. Azizi
背景
异常子宫出血（AUB）是育龄妇女最常见的妇科疾病之一。本研究的目的是调查伊朗育龄妇女AUB的患病率及其相关因素。
方法
对2009 - 2012年参加德黑兰血脂和葡萄糖研究的1393名15 - 45岁女性进行了一项基于人群的横断面研究。使用FIGO术语和先前定义对AUB进行分类。采用逻辑回归估计调整后的比值比（OR）和95%置信区间，以检查AUB与妇女人口统计学特征之间的关联。P < 0.05为有统计学意义。
结果
共有35.8%（95% CI：31.5% - 40.2%）的参与者患有一种或多种类型的AUB。约10.6%（95%CI：6.3% - 12.5%）的患者有规律性障碍，23.8%（95%CI：18.4% - 26.1%）的患者报告有频率障碍。此外，分别有16%（95% CI：12.7% - 19.2%）和11.5%（95% CI：8% - 15.4%）的患者报告了血流沉重和血流持续时间紊乱。约4.3%的女性（95% CI：2.1% - 10.5%）报告了不规则的非月经出血。根据以往的定义，育龄妇女月经过多、崩漏、月经过多、月经过少、闭经和经间期出血的患病率分别为15.2%、18.9%、10.6%、15.2%、2.2%和4.3%。此外，患有AUB的女性比例在生育早期和晚期都有所上升。校正混杂因素后，Logistic回归分析显示年龄（校正OR = 1.08，95%CI：1.07 - 3.97，P = 0.03）和BMI（校正OR = 1.05，95%CI：1.02 - 3.04，P = 0.04）与AUB有统计学意义的相关性。
结论
作为潜在疾病的可能临床指标，AUB的患病率在伊朗育龄妇女中很高。卫生保健提供者和政策制定者必须承认这些疾病，并为公众提供教育和咨询机会，告知他们何时以及如何寻求医疗建议。
BACKGROUND
Abnormal uterine bleeding (AUB) is one of the most common gynecologic complaints among reproductive-age women. The purpose of this study was to investigate the prevalence of AUB and its related factors among reproductive age Iranian women.
METHODS
A population-based cross-sectional study was conducted on 1393 women aged 15 - 45 years who participated in the Tehran Lipid and Glucose Study in 2009 - 2012. FIGO terminology and previous definitions were used for classification of AUB. Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals to check the association between AUB and the women's demographic characteristics. P < 0.05 was considered statistically significant.
RESULTS
A total of 35.8% (95% CI: 31.5% - 40.2%) of the participants suffered from one or more types of AUB. About 10.6% (95% CI: 6.3% - 12.5%) of them had disturbances of regularity and 23.8% (95% CI: 18.4% - 26.1%) reported experiencing disturbances of frequency. Also, disturbances of heaviness of flow and duration of flow were reported in 16% (95% CI: 12.7% - 19.2%) and 11.5% (95% CI: 8% - 15.4%), respectively. About 4.3% of the women (95% CI: 2.1% - 10.5%) reported irregular non-menstrual bleeding. According to previous definitions, the prevalence of heavy periods, metrorrhagia, polymenorrhea, oligomenorrhea, amenorrhea and inter-menstrual bleeding in reproductive aged women was 15.2%, 18.9%, 10.6%, 15.2%, 2.2%, and 4.3%, respectively. In addition, the proportions of women with AUB rose in the early and late reproductive years. After adjustment of confounders, logistic regression analysis showed that age (adjusted OR = 1.08, 95% CI: 1.07 - 3.97, P = 0.03) and BMI (adjusted OR = 1.05, 95% CI: 1.02 - 3.04, P = 0.04) had statistically significant associations with AUB.
CONCLUSION
The prevalence of AUB as a possible clinical indicator of underlying disorders was high among Iranian reproductive age women. Healthcare providers and policy makers are required to acknowledge these disorders and provide education and counseling opportunities for the public to inform them when and how to seek medical advice.