Cross-sectional associations of C-reactive protein with vascular risk factors and vascular complications in the DCCT/EDIC cohort
Cross-sectional associations of C-reactive protein with vascular risk factors and vascular complications in the DCCT/EDIC cohort
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DOI：
10.1016/j.jdiacomp.2007.02.003
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发表时间：
2008-05-01
影响因子：
3
通讯作者：
Lyons, Timothy J.
中科院分区：
文献类型：
--
作者：
Jenkins, Alicia J.;Rothen, Michelle;Lyons, Timothy J.
目的：探讨C反应蛋白（CRP）水平与1型糖尿病临床特征的关系。研究设计和方法：在糖尿病控制和并发症试验/糖尿病干预和并发症流行病学（DCCT/EDIC）队列（n=983）和非糖尿病受试者（n=71）的横断面研究中，通过浊度法测定血清CRP。结果：糖尿病受试者的CRP水平[几何平均值（95% CI）]高于对照受试者，1.6（1.5-1.7）vs. 1.2（1.1-1.5）mg/l，P= 0.019。女性糖尿病患者（n=438）CRP水平高于男性糖尿病患者（n=545）[2.0（1.8-2.3）vs. 1.3（1.2-1.5），P
Objective: To determine the relationships between C-reactive protein (CRP) levels and features of Type 1 diabetes. Research Design and Methods: Serum CRP was measured by nephelometry in a cross-sectional study of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) cohort (n=983) and nondiabetic subjects (n=71). Results: CRP levels [geometric mean (95% CI)] were higher in diabetic than in control subjects, 1.6 (1.5-1.7) vs. 1.2 (1.1-1.5) mg/l, P=.019. CRP was higher in diabetic women (n=438) than in men (n=545) [2.0 (1.8-2.3) vs. 1.3 (1.2-1.5), P