The effect of the presence of foreign salts on the formation of gaseous ions for electrospray and laser spray
The effect of the presence of foreign salts on the formation of gaseous ions for electrospray and laser spray
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DOI：
10.1002/rcm.1644
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发表时间：
2004-01-01
影响因子：
2
通讯作者：
Takamizawa, A
中科院分区：
文献类型：
--
作者：
Hiraoka, K;Asakawa, Y;Takamizawa, A
研究了外来盐（NaCl、气溶胶 OT、四正己基溴化铵和 CH3COONH4）的存在对电喷雾 (ES) 和激光喷雾 (LS) 气态离子形成的影响，并在正负操作模式下进行了研究。对于 ES 和 LS，氨基酸的离子信号随着外源盐浓度大于 10(-5) M 而突然降低。添加表面活性抗衡离子后，ES 和 LS 的信号强度均显着下降。这可能是由于带电液滴表面上表面活性反离子的富集。当将CH 3 COONH 4 添加到10(-6)M氯化溶菌酶的水溶液中时，观察到(溶菌酶+nH)(n+)的信号强度增加和n值减少。 n 的减少可能是由于(溶菌酶+nH)(n+)与负乙酸根离子形成盐导致正电荷减少。版权所有 (C) 2004 John Wiley Sons, Ltd.
The effect of the presence of foreign salts (NaCl, aerosol OT, tetra-n-hexylammonium bromide, and CH3COONH4) on the formation of gaseous ions for electrospray (ES) and laser spray (LS) was studied in the positive and negative modes of operations. The ion signals for amino acids show sudden decrease with the concentration of foreign salts greater than 10(-5) M for both ES and LS. When the surface-active counter ions were added, the signal intensities showed a marked decrease for both ES and LS. This may be due to the enrichment of the surface-active counter ions on the surface of the charged droplets. When CH3COONH4 was added to an aqueous solution of 10(-6) M lysozyme chloride, an increase of the signal intensities for (lysozyme+nH)(n+) and a decrease in the values of n were observed. The decrease in n may be due to the salt formation of (lysozyme+nH)(n+) with the negative acetate ion leading to the reduction of positive charges. Copyright (C) 2004 John Wiley Sons, Ltd.