STUDIES ON PEPTIDE ANTIBIOTICS, LEUCINOSTATINS .1. SEPARATION, PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL-ACTIVITIES OF LEUCINOSTATIN-A AND LEUCINOSTATIN-B
STUDIES ON PEPTIDE ANTIBIOTICS, LEUCINOSTATINS .1. SEPARATION, PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL-ACTIVITIES OF LEUCINOSTATIN-A AND LEUCINOSTATIN-B
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DOI：
10.7164/antibiotics.36.1606
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发表时间：
1983-01-01
影响因子：
3.3
通讯作者：
SUZUKI, M
中科院分区：
文献类型：
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作者：
FUKUSHIMA, K;ARAI, T;SUZUKI, M
亮氨酸抑素是一种多肽抗生素，经硅胶和氧化铝柱层析分离得到2个相关组分，分别命名为亮氨酸抑素A盐酸盐(C61H111N11O13.cntdot.HCl)和亮氨酸抑素B盐酸盐(C61H109N11O13.cntdot.HCl)。对分离出的2个组分进行了理化和生物学特性[抗真菌、抗菌]分析。这些性质表明了相似的化学结构。
Leucinostatin, a peptide antibiotic, was separated by silica gel and alumina column chromatography into 2 related components designated as leucinostatin A hydrochloride (C61H111N11O13.cntdot.HCl) and leucinostatin B hydrochloride (C61H109N11O13.cntdot.HCl). Physicochemical and biological properties [antifungal, antibacterial] of the 2 separated components were analyzed. These properties suggested similar chemical structures.