EFFECT OF DIETARY-INTAKE OF FREEZE-DRIED BITTER GOURD (MOMORDICA-CHARANTIA) IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
EFFECT OF DIETARY-INTAKE OF FREEZE-DRIED BITTER GOURD (MOMORDICA-CHARANTIA) IN STREPTOZOTOCIN-INDUCED DIABETIC RATS
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DOI：
10.1002/food.19950390403
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发表时间：
1995-01-01
期刊：
影响因子：
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通讯作者：
SRINIVASAN, K
中科院分区：
文献类型：
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作者：
PLATEL, K;SRINIVASAN, K
糖尿病患者食用苦瓜（Momordica charantia）在印度是一种常见的做法，人们相信它具有有用的降血糖潜力。在没有结论性的信息连续摄入苦瓜的降血糖影响，在目前的调查中，我们已经研究了实验诱导的糖尿病大鼠的饮食苦瓜的降血糖效力。Wistar大鼠通过链脲佐菌素（50 mg/kg b.w.，注射用）以半合成饲料（含0.5%苦瓜粉）饲养6周。在实验期间监测葡萄糖、蛋白质、尿素和肌酐的排泄。在实验方案结束时分析血浆葡萄糖、白蛋白、尿素和胆固醇。饮食苦瓜并没有显示出任何有益的降血糖的影响，证明了血糖水平以及糖尿病相关代谢物的排泄。
Consumption of bitter gourd (Momordica charantia) by diabetic patients is a common practice in India, with the belief that it has an useful hypoglycemic potential. In the absence of conclusive information on the hypoglycemic influence of continuous intake of bitter gourd, in the present investigation, we have examined the hypoglycemic potency of dietary bitter gourd in experimentally induced diabetic rats. Wistar rats rendered hyperglycemic by streptozotocin (50 mg/kg b.w., i.p.) were maintained on a semi-synthetic diet containing freeze dried bitter gourd powder at 0.5% Level for 6 weeks. The excretion of glucose, protein, urea and creatinine was monitored during the experimental period. Plasma glucose, albumin, urea and cholesterol were analysed at the end of the experimental regime. Dietary bitter gourd did not show any beneficial hypoglycemic influence as evidenced by the blood glucose levels as well as the excretion of diabetes related metabolites.