A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder.

A systematic literature review of patient perspectives of barriers and facilitators to access, adherence, stigma, and persistence to treatment for substance use disorder.
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DOI:
10.1016/j.rcsop.2021.100029
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发表时间:
2021-06
期刊:
EXPLORATORY RESEARCH IN CLINICAL AND SOCIAL PHARMACY
影响因子:
--
通讯作者:
Gatwood, Justin
Gatwood, Justin
中科院分区:
其他
文献类型:
--
作者:
Cernasev, Alina;Hohmeier, Kenneth C.;Frederick, Kelsey;Jasmin, Hilary;Gatwood, Justin

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阿片类药物危机给美国(美国)留下了毁灭性的影响。已经20多年了。阿片类药物的过度处方和非法阿片类药物的可获得性导致了美国阿片类药物的流行。鉴于疫情、物质使用障碍及其治疗的复杂性,迫切需要对捕捉患者经历的定性文献进行彻底审查,这些患者获得的关于生活经验和观点的定性数据可能会使研究人员、临床医生和政策制定者收集新的见解来应对这一流行病。本文的目的是对美国现有的定性研究进行系统的文献综述,并从患者的角度看待阿片类药物使用障碍(Moud)的药物,包括障碍和促进剂。2019年11月,医学图书馆员使用关键词、医学主题词(MESH)和/或CINAHL主题词的组合搜索了四个电子数据库(PubMed、CINAHL、Scope us和Web of Science)。将8766个结果导入Endnote,然后删除重复记录,共保留4722篇文章。这些独特的记录被导入到Rayyan QCRI,这是一个旨在加快筛查的在线平台。盲法筛选由四名评价者一式两份进行。两名研究人员对所有文章进行了提炼,并进行了主题分析。摘要阶段的筛选排除了4681项结果,剩下41项研究进行全文筛选,以确定它们是否符合纳入审查的条件。经过筛选,该研究纳入了21篇文章,并基于这些文章进行了分析。研究中的共同主题包括污名化、穆德的感知障碍、穆德治疗沙漠和提供者短缺。迄今为止进行的定性研究揭示了大量的Moud待遇障碍,这些障碍既有社会性质的,也有结构性的。这种治疗障碍可能会加剧目前的流行病,在为OUD患者制定政策和治疗解决方案时必须考虑到这一点。
The opioid crisis has left a devastating impact on the United States (U.S.) for over 20 years. The over-prescribing of opioid medications and availability of illicit opioids have contributed to the U.S. opioid epidemic. Given the complexity of the epidemic, substance use disorder, and its treatment, there is an urgent need for a thorough review of the qualitative literature which has captured the patient's experiences Such patient-derived qualitative data on lived experiences and perspectives may allow researchers, clinicians, and policy makers to glean new insights into addressing this epidemic. The objective of this paper is to present a systematic literature review of the existing U.S. qualitative research and provide a patient perspective on medications for opioid use disorder (MOUD), including barriers and facilitators to MOUD use. In November 2019, four electronic databases (PubMed, CINAHL, Scopus, and Web of Science) were searched by a medical librarian using a combination of keywords, Medical Subject Headings (MeSH), and/or CINAHL subject headings. 8766 results were imported into EndNote, then duplicate records were removed, leaving a total of 4722 articles. The unique records were imported into Rayyan QCRI an online platform designed to expedite screening. Blinded screening was undertaken in duplicate by four reviewers. Two researchers abstracted all the articles and used thematic analysis. The screening in the abstract phase excluded 4681 results, leaving 41 studies for full-text screening to determine their eligibility for inclusion in the review. After screening, 21 articles were included in the study and the analysis is based on these articles Common themes across studies included stigmatization, perceived barriers to MOUD, and MOUD treatment deserts and provider shortages. Qualitative research studies conducted to date have uncovered substantial MOUD treatment barriers which are both social and structural in nature. Such barriers to treatment may serve to exacerbate the current epidemic and must be taken into consideration in designing policy and treatment solutions for patients with OUD.
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