Clinical and histopathological findings in two Turkish children with follicular bronchiolitis

Clinical and histopathological findings in two Turkish children with follicular bronchiolitis
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DOI:
10.1007/pl00008432
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发表时间:
2001-04-01
影响因子:
3.6
通讯作者:
Zach, MS
Zach, MS
中科院分区:
医学3区
文献类型:
--
作者:
Benesch, M;Kurz, H;Zach, MS

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我们报告了两名土耳其儿童,他们表现为进行性呼吸道阻塞。开胸肺活检显示毛细支气管炎。这些儿童接受了全身类固醇和各种局部药物的治疗。而患者1的呼吸情况需要免疫抑制治疗,患者2的情况在没有全身药物治疗的情况下稳定下来。结论当儿童出现反复呼吸道感染、进行性呼吸困难和慢性支气管阻塞时,应考虑毛细支气管炎的诊断。怀疑毛细支气管炎的儿童应接受开胸肺活检以确认诊断。
We report on two Turkish children who presented with progressive airway obstruction. Open lung biopsy revealed follicular bronchiolitis. The children were treated with systemic steroids and various topical medications. Whereas the respiratory situation of patient 1 required immunosuppressive therapy, the condition of patient 2 stabilised without systemic medication.Conclusion Diagnosis of follicular bronchiolitis should be considered when children present with recurrent respiratory tract infections, progressive dyspnoea, and chronic bronchial obstruction. Children in whom follicular bronchiolitis is suspected should undergo open lung biopsy for confirmation of diagnosis.