Morphological properties of chick retinal ganglion cells in relation to their central projections
Morphological properties of chick retinal ganglion cells in relation to their central projections
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DOI：
10.1002/cne.21995
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发表时间：
2009-05
影响因子：
2.5
通讯作者：
Yaoxing Chen;J. Naito
中科院分区：
文献类型：
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作者：
Yaoxing Chen;J. Naito
对23只雏鸡视网膜神经节细胞(RGC)的形态特征及其与中枢投射的关系进行了研究。将碳菁染料(DiI)逆行标记于丘脑和视顶盖，共217个视网膜节细胞。标记的视网膜节细胞根据其胞体面积、树突区和分支模式被分为六组。这些RGC的树突在内丛状层(IPL)水平延伸，形成8个树枝状层。每组的视网膜节细胞在其中央投射中表现出一定的特异性。IC组主要投射到顶盖。IIs组和IIIs组丘脑优势度较高。IS组和IIc组在顶盖和丘脑投射方面没有特异性。IVC组显示顶盖特定的投射。树枝状层的出现率由高到低依次为树枝状层1~4，树枝状层5、6中等分布，树枝状层7、8分布最频繁。共鉴定出42种树突分层模式，其中18种模式是顶盖视网膜节细胞(TEC-RGCs)和丘脑视网膜节细胞(THA-RGCs)共有的。在TEC和THA-RGC中发现常见的模式(≈85%)，树突层主要分布在IPL的内侧(DSS5-8)。相反，其余24种非常见层结模式的出现率很低(≈15%)，但这些树枝状地层广泛分布在外部(DSS1-4)和内部(DSS5-8)IPL。J.Comp.神经。514：117-130,2009。©2009威利-利斯，Inc.
Morphological properties of chick retinal ganglion cells (RGCs) were studied in relation to their central projections in 23 chicks. A total of 217 RGCs were retrogradely labeled by applying a carbocyanine dye (DiI) to the thalamus and optic tectum. The labeled RGCs were classified into six groups on the basis of their somal areas, dendritic fields, and branching patterns. The dendrites of these RGCs extended horizontally in the inner plexiform layer (IPL) forming eight dendritic strata. The RGCs in each group showed certain specificities in their central projections. Group Ic predominantly projected to the tectum. Groups IIs and IIIs showed a high thalamic dominance. Groups Is and IIc were nonspecific with regard to their tectal and thalamic projections. Group IVc showed tectal‐specific projections. Occurrence rates of the dendritic strata increased progressively toward the inner part of the IPL, i.e., DSs (dendritic strata) 1–4 were scantily distributed, DSs 5 and 6 were moderately distributed, and DSs 7 and 8 were the most frequently distributed. A total of 42 dendritic stratification patterns were identified, and of these, 18 patterns were common to the tectal RGCs (tec‐RGCs) and thalamic RGCs (tha‐RGCs). The common patterns were detected very frequently in the tec‐ and tha‐RGCs (≈85%), and the dendritic strata were largely distributed in the inner part of the IPL (DSs 5–8). In contrast, the remaining 24 noncommon stratification patterns showed low occurrence rates (≈15%); however, these dendritic strata were widely distributed in both the outer (DSs 1–4) and inner (DSs 5–8) IPL. J. Comp. Neurol. 514:117–130, 2009. © 2009 Wiley‐Liss, Inc.