The central nervous origin of the swimming motor pattern in embryos of Xenopus laevis.
The central nervous origin of the swimming motor pattern in embryos of Xenopus laevis.
复制标题
非洲爪蟾胚胎游泳运动模式的中枢神经起源。
DOI：
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发表时间：
1982
影响因子：
2.8
通讯作者：
A. Roberts
中科院分区：
文献类型：
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作者：
J. A. Kahn;A. Roberts
在用箭毒麻痹的 37/38 期非洲爪蟾胚胎中记录节律性运动神经活动。该活动在以下方面与游泳运动模式相似：循环周期（40-125 毫秒）、节段两侧的活动交替、头尾阶段滞后。节律性运动活动的发作可以由引起游泳的刺激引起，并由通常抑制游泳的刺激抑制。在此基础上，我们得出结论，游泳运动模式是由中枢神经机制产生的，不依赖于感觉反馈。除了游泳模式外，有时在箭毒胚胎中还记录到另一种运动活动模式（“同步”）。在这种情况下，节律两侧的节律爆发是同步发生的，节律周期（20-50毫秒）是游泳时的一半。这可能不是箭毒化的产物，因为有迹象表明在未箭化的胚胎中存在类似的模式。其功能仍不清楚。
Rhythmic motor nerve activity was recorded in stage 37/38 Xenopus embryos paralysed with curare. The activity was similar to the swimming motor pattern in the following ways: cycle period (40-125 ms), alternation of activity on either side of a segment, rostro-caudal phase lag. Episodes of rhythmic motor activity could be evoked by stimuli that evoke swimming and inhibited by stimuli that normally inhibit swimming. On this basis we conclude that the swimming motor pattern is generated by a central nervous mechanism and is not dependent on sensory feedback. In addition to the swimming pattern, another pattern of motor activity ('synchrony') was sometimes recorded in curarized embryos. In this, the rhythmic bursts on either side of a segment occurred in synchrony, and the rhythm period (20-50 ms) was half that in swimming. This was probably not an artifact of curarization as there were indications of a similar pattern in uncurarized embryos. Its function remains unclear.