Metacarpal radiogrammetry by computed radiography in postmenopausal women with Colles' fracture and vertebral crush fracture syndrome
Metacarpal radiogrammetry by computed radiography in postmenopausal women with Colles' fracture and vertebral crush fracture syndrome
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DOI：
10.1007/s002239900463
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发表时间：
1998-05-01
影响因子：
4.2
通讯作者：
Rico, H
中科院分区：
文献类型：
--
作者：
Crespo, R;Revilla, M;Rico, H
基于绝经后妇女Colles骨折的潜在骨质疏松机制与其他骨质疏松性骨折相似的假设，即皮质骨吸收而不是松质骨吸收，比较了40名正常绝经后妇女的皮质骨内膜骨丢失率[平均年龄68.4 ± 7.1岁;绝经后20 +/- 4年（YSM）]，35例绝经后Colles骨折妇女（年龄69.4 +/- 7.5岁，22 +/- 8 YSM），在35例正常绝经后椎体粉碎性骨折妇女中（年龄69.4 ± 7.5岁，22 ± 8 YSM）和35名正常绝经前妇女（年龄36.1 ± 7.9岁）。通过第二掌骨的数字X线摄影进行X线摄影测量，以测量外径（艾德）和内径（ID）、皮质厚度（CCT）、皮质面积（CA）以及皮质面积与总面积的比值（CA/TA）。将绝经前妇女的ID值减去绝经后妇女组的ID值，并将结果除以YSM，以获得皮质骨内膜吸收/年（Delta C）、CA吸收年（Delta CA）和CA/TA吸收/年（Delta CA/ TA）。Colles骨折和椎体挤压骨折的绝经后妇女的ID、Delta C、Delta CA和Delta CA/TA均大于正常绝经后妇女（ANOVA：均P < 0.0001）。两组绝经后骨折妇女的ID、CCT、Delta C、CA、Delta CA和Delta CA/TA无差异。与正常绝经后妇女相比，椎体粉碎性骨折的绝经后妇女的δ C值高87%，Colles骨折的妇女高116%。这些结果表明，皮质骨丢失是绝经后妇女Colles骨折的一个重要因素。
Based on the hypothesis that the underlying osteoporotic mechanism of Colles' fracture in postmenopausal women is similar to that of other osteoporotic fractures, that is, cortical bone resorption as opposed to cancellous bone resorption, the rate of corticoendosteal bone loss was compared in 40 normal postmenopausal women [average age 68.4 +/- 7.1 years; 20 +/- 4 years since menopause (YSM)], in 35 postmenopausal women with Colles' fracture (age 69.4 +/- 7.5 years, 22 +/- 8 YSM), in 35 normal postmenopausal women with vertebral crush fracture (age 69.4 +/- 7.5 years, 22 +/- 8 YSM, and in 35 normal premenopausal women (age 36.1 +/- 7.9 years). Radiogrammetry by digital radiography of the second metacarpal was used to measure external (ED) and internal (ID) diameter, cortical thickness (CCT), cortical area (CA), and the ratio of cortical area to total area (CA/TA). The ID values of the groups of postmenopausal women were subtracted from the ID value of the premenopausal women and the result was divided by YSM to obtain the rate of corticoendosteal resorption/year (Delta C), CA resorption year (Delta CA) and CA/TA resorption/year (Delta CA/ TA). ID, Delta C, Delta CA, and Delta CA/TA all were larger in the postmenopausal women with Colles' and vertebral crush fractures than in the normal postmenopausal women (ANOVA: all P < 0.0001). ID, CCT, Delta C, CA, Delta CA, and Delta CA/TA did not differ between the two groups of postmenopausal women with fractures. Delta C was 87% greater in postmenopausal women with vertebral crush fracture and 116% greater in women with Colles' fracture than in normal postmenopausal women. These results indicate that the loss of cortical bone is an important factor in Colles' fracture in postmenopausal women.