Disorders of excessive daytime somnolence: polygraphic and clinical data for 100 patients.
Disorders of excessive daytime somnolence: polygraphic and clinical data for 100 patients.
复制标题
白天过度嗜睡疾病：100 名患者的测绘和临床数据。
作者：
J. Hoed;Helena C. Kraemer;Christian Guilleminault;Vincent P. Zarcone;L. Miles;W. C. Dement;M. M. Mitler
对 100 名无睡眠呼吸暂停且主诉白天过度嗜睡 (EDS) 的患者进行了连续系列评估；来自病史、体检、性格调查和多导睡眠图[夜间多导睡眠图（NPSG）和日间多次睡眠潜伏期测试（MSLT）]的数据被制成表格。发作性睡病患者和非发作性睡病患者在许多参数上均发现显着差异，包括 EDS 严重程度、MSLT 平均睡眠潜伏期、NPSG 睡眠潜伏期、夜间 REM 睡眠潜伏期、夜间 REM 睡眠次数、整夜 REM 睡眠段数、夜间肌阵挛性抽搐总数（以及 NREM 和 REM 睡眠每小时发生的次数）以及之前的觉醒和觉醒期次数。肌阵挛性抽搐。在非发作性睡病患者的不同 EDS 诊断组之间发现 MSLT 和 NPSG 测试期间睡眠潜伏期存在显着差异。 MSLT 组中睡眠潜伏期较长的大多数患者属于与心理生理和/或精神问题或药物滥用相关的 EDS 诊断组；被诊断为特发性中枢神经系统嗜睡症或与夜间睡眠障碍相关的 EDS 的患者构成了睡眠潜伏期短的 MSLT 组的大多数。与长睡眠潜伏期患者相比，短睡眠潜伏期 MSLT 组中的非发作性睡病患者夜间睡眠潜伏期明显更短、睡眠周期更多、睡眠效率更高、快速眼动睡眠更早。
A consecutive series of 100 sleep apnea free patients with the complaint of excessive daytime somnolence (EDS) were evaluated; data from medical histories, physical examination, personality inventories, and polysomnography [nocturnal polysomnography (NPSG) and daytime multiple sleep latency testing (MSLT)] were tabulated. Significant differences were found between narcoleptic and non-narcoleptic patients in a number of parameters, including EDS severity, mean sleep latency on MSLT, sleep latency on NPSG, latency to REM sleep at night, number of REM sleep at night, number of REM sleep segments throughout the night, the total number of nocturnal myoclonic jerks (as well as the number occurring per hour of NREM and REM sleep), and the number of arousals and wake periods preceded by a myoclonic jerk. Significant differences in sleep latency during MSLT and NPSG testing were found between different EDS diagnostic groups of non-narcoleptic patients. The majority of patients in the MSLT group with long sleep latencies were in the diagnostic groups of EDS associated with psychophysiological and/or psychiatric problems or with drug abuse; patients with a diagnosis of idiopathic central nervous system hypersomnia or EDS associated with disturbed nocturnal sleep formed the majority of the MSLT group with short sleep latencies. The non-narcoleptic patients in a MSLT group with short sleep latencies had significantly shorter sleep latencies at night, more sleep cycles, higher sleep efficiency, and earlier REM sleep than patients with long sleep latencies.