Epidemiological survey of intraocular inflammation in Japan
Epidemiological survey of intraocular inflammation in Japan
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DOI：
10.1007/s10384-006-0383-4
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发表时间：
2007-01-01
影响因子：
2.4
通讯作者：
Ohno, Shigeaki
中科院分区：
文献类型：
--
作者：
Goto, Hiroshi;Mochizuki, Manabu;Ohno, Shigeaki
目的：根据2002年日本大学医院眼科新患者就诊调查报告眼内炎症的频率和趋势。方法：对全国110所大学医院眼科进行问卷调查，了解2002年1月1日至12月31日首次就诊的新患者总数，结果：本研究分析了41所大学医院完成的调查。2002年，41家机构共收治了151，299名新眼科患者，其中3，060名（2.2%）被诊断出患有眼内炎症。最常见的眼内炎性疾病是结节病（13.3%），其次是Vogt-Koyanagi-Harada（VKH）病（6.7%），白塞氏病细菌性眼内炎6.2%疱疹性虹膜睫状体炎3.8%（3.6%），糖尿病虹膜炎（1.6%），人类白细胞抗原-B27相关性葡萄膜炎（1.5%）、急性视网膜坏死（1.3%）、眼弓形虫病（1.1%）、眼弓形虫病（1.1%）、与人T淋巴细胞病毒-1（也称为HAU）相关的葡萄膜炎（1.1%）等。感染性眼内炎症占所有葡萄膜炎cases.Conclusions的16%：通过大量的机构的合作，在日本的眼内炎症的流行病学的某些方面进行了阐述。然而，对于眼内炎症范围内的相当多的疾病，疾病概念和诊断标准仍然模糊不清，并且不能否认这些因素可能会使本研究结果产生偏差的可能性。今后，需要根据明确界定的共同诊断标准进行前瞻性调查，以获得更准确的流行病学数据。
Purpose: To report the frequency and trend of intraocular inflammation based on a survey of new ophthalmology patient visits to university hospitals throughout Japan during 2002.Methods: A questionnaire was sent to the departments of ophthalmology in 110 university hospitals nationwide to survey the total number of new patients who visited the outpatient clinics for the first time between 1 January and 31 December 2002, and also the number of patients diagnosed with intraocular inflammation during this period.Results: The surveys completed by 41 university hospitals were analyzed in this study. During 2002, a total of 151 299 new ophthalmological patients presented at the 41 institutions, and 3060 (2.2%) of the new patients were diagnosed as having intraocular inflammation. The most frequent intraocular inflammatory disease identified was sarcoidosis (13.3%), followed by Vogt-Koyanagi-Harada (VKH) disease (6.7%), Behcet disease (6.2%), bacterial endophthalmitis (3.8%), herpetic iridocyclitis (3.6%), diabetic iritis (1.6%), human leukocyte antigen-B27-associated uveitis (1.5%), acute retinal necrosis (1.3%), ocular toxoplasmosis (1.1%), ocular toxocariasis (1.1%), uveitis associated with human T lymphotropic virus-1 (also known as HAU) (1.1%), and others. Infectious intraocular inflammation accounted for 16% of all uveitis cases.Conclusions: Through the collaboration of a large number of institutions, some aspects of the epidemiology of intraocular inflammation in Japan were elucidated. However, the disease concept and diagnostic criteria remain ambiguous for a considerable number of diseases within the spectrum of intraocular inflammation, and the possibility that such factors may bias the present findings cannot be denied. In the future, a prospective survey based on well-defined, common diagnostic criteria is required to obtain more precise epidemiological data.