Differential regulation of elevated renal angiotensin II in chronic renal ischemia
Differential regulation of elevated renal angiotensin II in chronic renal ischemia
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DOI：
10.1161/01.hyp.0000022060.13995.ed
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发表时间：
2002-07-01
期刊：
影响因子：
8.3
通讯作者：
Saruta, T
中科院分区：
文献类型：
--
作者：
Tokuyama, H;Hayashi, K;Saruta, T
本研究旨在阐明肾内血管紧张素(Ang)IF在麻醉犬单侧肾动脉狭窄4周夹闭和非夹闭肾脏中的作用及其发生途径。4周后，夹肾和未夹肾的肾血浆流量(RPF)均下降(基线，59+/-3；夹肾，16+/-1；未夹肾)。44+/-2mL/min；P
The present study was undertaken to clarify the role of intrarenal angiotensin (Ang) If and its generating pathways in clipped and nonclipped kidneys of 4-week unilateral renal artery stenosis in anesthetized dogs. After 4 weeks, renal plasma flow (RPF) decreased in clipped and nonclipped kidneys (baseline, 59 +/- 3; clipped, 16 +/- 1; nonclipped. 44 +/- 2 mL/min; P