Analysis of Thermoplastic Copolymers by Mild Thermal Degradation Coupled to Ion Mobility Mass Spectrometry
Analysis of Thermoplastic Copolymers by Mild Thermal Degradation Coupled to Ion Mobility Mass Spectrometry
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通过轻度热降解与离子淌度质谱联用分析热塑性共聚物
DOI：
10.1002/marc.202200306
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发表时间：
2022
影响因子：
4.6
通讯作者：
Wesdemiotis, Chrys
中科院分区：
文献类型：
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作者：
Alawani, Nadrah;Barrère‐Mangote, Caroline;Wesdemiotis, Chrys
利用大气固体分析探头(ASAP)的热解吸/降解和离子迁移率(IM)分离，结合质谱仪(MS)分析和串联质谱仪(MS/MS)裂解来表征热塑性弹性体。所研究的化合物用于制造各种包装材料，主要由热塑性共聚物组成，但也含有额外的化学品(“添加剂”)，如抗氧化剂和紫外线稳定剂，以增强其性能或防止降解。分析这种复杂混合物的传统方法是真空热解，然后是电子或化学电离质谱仪，通常是在气相色谱分离之后。在这里，提出了一种替代的、更快的方法，包括在常压(ASAP)下温和降解，然后用IM-MS表征解吸和裂解产物，如果需要，还可以用MS/MS。这种多维分散大大简化了所产生的光谱，允许对所研究的多组分材料进行决定性的分离、表征和分类。
Thermal desorption/degradation with an atmospheric solids analysis probe (ASAP) and ion mobility (IM) separation are coupled with mass spectrometry (MS) analysis and tandem mass spectrometry (MS/MS) fragmentation to characterize thermoplastic elastomers. The compounds investigated, which are used in the manufacture of a wide variety of packaging materials, are mainly composed of thermoplastic copolymers, but also contain additional chemicals (“additives”), like antioxidants and UV stabilizers, for enhancement of their properties or protection from degradation. The traditional method for analyzing such complex mixtures is vacuum pyrolysis followed by electron or chemical ionization mass spectrometry, often after gas chromatography separation. Here, an alternative, faster approach, involving mild degradation at atmospheric pressure (ASAP) and subsequent characterization of the desorbates and pyrolyzates by IM‐MS, and if needed, MS/MS is presented. Such multidimensional dispersion considerably simplifies the resulting spectra, permitting the conclusive separation, characterization, and classification of the multicomponent materials examined.