Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure
Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure
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DOI：
10.1227/01.neu.0000249194.76527.28
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发表时间：
2007-01-01
期刊：
影响因子：
4.8
通讯作者：
Fainardi, Enrico
中科院分区：
文献类型：
--
作者：
Chieregato, Arturo;Tanfani, Alessandra;Fainardi, Enrico
目的：评价脑挫伤水肿区局部脑血流量(RCBF)急性升高的反应。方法：rCBF是在挫伤灶内低密度区、挫伤周围正常脑组织、健侧大脑半球、16例颅脑损伤患者中，16例创伤性挫伤后基线大于2 cm的患者，在非肾上腺素诱导的20分钟后，CPP水平从基线值65.8ml/100g/min(标准差，标准差，下同)开始升高。608)到最终值88.7ml/100g/min(标准差，8.6)到最终值88.7ml/100g/min(标准差，8.9；P
Objective: To evaluate the response to an acute elevation of cerebral perfusion pressure (CPP) of the regional cerebral blood flow (rCBF) measured in the edematous area of traumatic contusions.Methods: rCBF was measures in the intracontusional low-density area, in the pericontusional healthy-appearing brain tissue surrounding the contusion, in a healthy-appearing area in he contralateral hemisphere, in 16 head-injured patients with 16 traumatic contusions larger than 2 cm at the baseline, and after 20 minutes of nonrepinephrine-induced 20-mmHg elevation of CPP levels.Results: After an induced acute elevation of CPP from baseline values of 65.8 ml/100 g/min (standard deviation, 608) to final values of 88.7 ml/100 g/min (standard deviation, 8.6) to final values of 88.7 ml/100 g/min (standard deviation, 8.9; P