CHIRAL SYMMETRY-BREAKING IN SODIUM-CHLORATE CRYSTALLIZATION
CHIRAL SYMMETRY-BREAKING IN SODIUM-CHLORATE CRYSTALLIZATION
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DOI：
10.1126/science.250.4983.975
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发表时间：
1990-11-16
期刊：
影响因子：
56.9
通讯作者：
SINGH, N
中科院分区：
文献类型：
--
作者：
KONDEPUDI, DK;KAUFMAN, RJ;SINGH, N
氯酸钠（NaClO 3）晶体是光学活性的，尽管化合物的分子不是手性的。在不搅拌的情况下从水溶液中结晶时，发现左旋（L）和右旋（D）NaClO 3晶体的数量在统计学上是相等的，然而，当搅拌溶液时，几乎所有的NaClO 3晶体（99.7%）在一个特定的样品中具有相同的手性，左旋或右旋。这一结果代表了手性对称性破缺或总自发分辨率在宏观水平上所带来的自催化和L-和D-晶体之间的竞争的实验证明。
Sodium chlorate (NaClO3) crystals are optically active although the molecules of the compound are not chiral. When crystallized from an aqueous solution while the solution is not stirred, statistically equal numbers of levo (L) and dextro (D) NaClO3crystals were found. When the solution was stirred, however, almost all of the NaClO3crystals (99.7 percent) in a particular sample had the same chirality, either levo or dextro. This result represents an experimental demonstration of chiral symmetry breaking or total spontaneous resolution on a macroscopic level brought about by autocatalysis and competition between L- and D-crystals.