Evolution of functionality in lattice proteins
Evolution of functionality in lattice proteins
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DOI：
10.1016/s1093-3263(00)00125-x
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发表时间：
2001-01-01
影响因子：
2.9
通讯作者：
Goldstein, RA
中科院分区：
文献类型：
--
作者：
Williams, PD;Pollock, DD;Goldstein, RA
我们用二维格子模型研究了蛋白质功能的演化。演化所特有的特征，如种群动力学和早期演化轨迹，对观察到的结构分布有很大的影响。在为功能而进化的结构和为形成紧凑结构的能力而进化的结构的分布之间，只观察到细微的差异。(C)2001年，Elsevier Science Inc.
We study the evolution of protein functionality using a two-dimensional lattice model, The characteristics particular to evolution, such as population dynamics and early evolutionary; trajectories, have a large effect on the distribution of observed structures. Only subtle differences ai e observed between the distribution of structures evolved for function and those evolved for their ability to form compact structures. (C) 2001 by Elsevier Science Inc.