A prediction equation for total body water from bioelectrical impedance in Japanese children
A prediction equation for total body water from bioelectrical impedance in Japanese children
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DOI：
10.2114/jpa.23.35
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发表时间：
2004-03-01
期刊：
影响因子：
--
通讯作者：
Komiya, Shuichi
中科院分区：
文献类型：
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作者：
Masuda, Takashi;Komiya, Shuichi
采用同位素稀释法测定儿童体内总水分（TBW）可安全、准确地评价儿童的身体成分。不幸的是，这种方法并不适用于大多数研究项目，特别是在与大量人员合作时，因为设备复杂且高度专业化。生物电阻抗（BI）法是一种简单、快速、廉价的全身水分（TBW）测定方法。然而，在日本儿童人群中，缺乏预测方程是确定TBW的一个问题。本研究的目的是使用同位素稀释技术作为参考方法，确定日本儿童TBW测定的预测方程。70名年龄在3至6岁之间的日本儿童（39名男孩，31名女孩）参加了这项研究。被试被随机分为验证组（男26人，女20人）和交叉验证组（男13人，女11人）。在前向逐步回归分析中，通过氧化氘（D2 O）稀释测量的TBW的96%变异性可通过以下公式预测：TBW（kg）= 0.149x阻力指数（状态2/电阻，cm 2/Ω）+0.244 x体重（kg）+0.460 x年龄（y）+0.501 x性别（男孩=1，女孩=0）+1.628，验证组的均方根误差（RMSE）为0.440 kg。该方程预测交叉验证组中的TBW，R2=0.946，纯误差（PE）= 0.400 kg TBW。因此，这个方程应该适用于预测TBW在日本3-6岁的儿童。
Total body water (TBW) measured by isotope dilution techniques can be used to assess body composition safely and accurately in children. Unfortunately, this method is not readily available for most research projects, particularly when working with large groups of people, because the equipment is complicated and highly specialized. Bioelectrical impedance (BI) method is a simple, quick, and inexpensive method for the assessment of total body water (TBW). In Japanese child population, however, a lack of prediction equations is a problem to determine TBW. The purpose of this study was to determine the prediction equation for TBW determination in Japanese children using the isotope dilution technique as the reference method. Seventy Japanese children (39 boys, 31 girls) with ages ranging between 3 and 6 years participated in this study. They were randomly divided into the validation group (26 boys, 20 girls) and cross-validation group (13 boys, 11 girls). In a forward stepwise regression analysis, 96% of the variability in TBW measured by deuterium oxide (D2O) dilution could be predicted by the following equation: TBW(kg)=0.149xResistance Index (Stature2/resistance, cm2/OMEGA)+0.244x Weight(kg)+0.460xAge(y)+0.501xSex (boy=1, girl=0)+1.628, with a root mean square error (RMSE) of 0.440 kg in the validation group. This equation predicted TBW in the cross-validation group with R2=0.946 and a pure error (PE)=0.400kg TBW. Hence, this equation should be applicable for predicting TBW in Japanese children aged 3-6 y.