Cochlear implantation in adults with single-sided deafness: generic and disease-specific long-term quality of life
Cochlear implantation in adults with single-sided deafness: generic and disease-specific long-term quality of life
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DOI：
10.1007/s00405-019-05737-6
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发表时间：
2019-11-27
影响因子：
2.6
通讯作者：
Weichbold, Viktor W.
中科院分区：
文献类型：
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作者：
Muigg, Franz;Bliem, Harald R.;Weichbold, Viktor W.
目的：确定因单侧耳聋（SSD）接受人工耳蜗植入（CI）的成年人健康相关生活质量（HRQoL）的2年结果。方法：对20名单侧耳聋成年人（植入时平均年龄：47±11岁，患耳平均纯音听阈：113 dB HL，健耳平均纯音听阈：14 dB HL）采用奈梅亨人工耳蜗植入问卷（NCIQ）和健康效用指数3（HUI 3）进行评估。在人工耳蜗植入前以及植入激活后3、6、12和24个月进行问卷调查。结果：20名患者中，2名因效果不佳在观察期内停止使用人工耳蜗。样本的NCIQ总分随时间显著提高（p = 0.003），在使用人工耳蜗的前3个月内提高幅度最大。此外，HUI 3多属性效用评分也显著提高（p = 0.03）。该评分治疗后提高（+0.11分）表明HRQoL的提高具有临床相关性。耳聋持续时间>10年的患者在所有指标上与耳聋持续时间<10年的患者具有相同的HRQoL改善。结论：人工耳蜗植入使我们的患者在听力特异性和一般性HRQoL方面有显著改善。在3或6个月后即可看到改善，但在后期没有进一步提高。患有长期单侧耳聋的患者可能有更高的停止使用人工耳蜗的风险。然而，如果他们适应了人工耳蜗，他们可以像单侧耳聋持续时间较短的患者一样体验到HRQoL的同等提高。
Purpose To determine the 2-year outcome of health-related quality of life (HRQoL) in adults who received a cochlear implant (CI) for single-sided deafness (SSD). Methods Twenty adults (mean age at implantation: 47 +/- 11 years) with SSD (PTA worse ear: 113 dB HL, PTA better ear: 14 dB HL) were administered the Nijmegen Cochlear Implant Questionnaire (NCIQ), and the Health Utility Index 3 (HUI 3). Questionnaire administration occurred before cochlear implantation and 3, 6, 12, and 24 months after implant activation. Results Of the 20 patients, 2 discontinued CI use within the observation period due to poor benefit. The NCIQ total score of the sample increased significantly over time (p = 0.003). The largest increase occurred within the first 3 months of CI use. Also, the HUI 3 multi-attribute utility score increased significantly (p = 0.03). The post-treatment increase of this score (+ 0.11 points) indicated that the gain in HRQoL was clinically relevant. Patients with a duration of deafness > 10 years had in all measures an equal HRQoL improvement than had patients with a duration of deafness < 10 years. Conclusion Cochlear implantation led to significant improvement of hearing-specific and generic HRQoL in our patients. The improvement was seen after 3 or 6 months but did not increase further at later intervals. Patients with long-lasting SSD may be at higher risk of discontinuing CI use. However, if they adapt to the CI, they can experience an equal increase of HRQoL as patients with a short duration of SSD.