Electrochemically generated fluorescent fullerene[60] nanoparticles as a new and viable bioimaging platform
Electrochemically generated fluorescent fullerene[60] nanoparticles as a new and viable bioimaging platform
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电化学生成的荧光富勒烯[60]纳米粒子作为一种新的可行的生物成像平台
DOI：
10.1039/c0jm02492a
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发表时间：
2011-01-01
影响因子：
--
通讯作者：
Yang, Shihe
中科院分区：
文献类型：
--
作者：
E, Yifeng;Bai, Linling;Yang, Shihe
用电化学方法成功地制备了荧光超细C-60纳米粒子的水溶液，在乙腈溶液中，在四丁基铵(TBA(+))的存在下，将C-60薄膜还原为C-60(3-)阴离子并转移到水中。纳米粒子在可见光区具有很强的发射性。C-60荧光纳米粒子的结构类似于5 nm球体，具有聚集态C-60的固体核和C-60(3-)的阴离子外壳，这使得纳米粒子具有水溶性。光稳定性和无毒的C-60纳米颗粒可以很容易地渗透到活细胞中，因此为许多生物医学应用做好了准备。
Aqueous solutions of fluorescent ultrafine C-60 nanoparticles have been successfully prepared by an electrochemical method, which involves reducing a C-60 film to C-60(3-) anions in the presence of tetrabutylammonium (TBA(+)) cations in acetonitrile solution and transferring to water. The nanoparticles are highly emissive in the visible region. The structure of the fluorescent C-60 nanoparticles was deduced as a similar to 5 nm sphere with a solid core of aggregated C-60 and an anionic shell of C-60(3-), which renders the nanoparticles water soluble. The photostable and nontoxic C-60 nanoparticles can easily penetrate into live cells, and are thus primed for a host of biomedical applications.