Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China.
Prevalence of carbapenemases among high-level aminoglycoside-resistant Acinetobacter baumannii isolates in a university hospital in China.
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中国某大学医院高水平耐药鲍曼不动杆菌中碳青霉烯酶的患病率
DOI：
10.3892/etm.2016.3828
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发表时间：
2016-12
影响因子：
2.7
通讯作者：
Jia X
中科院分区：
文献类型：
--
作者：
Wang Y;Shen M;Yang J;Dai M;Chang Y;Zhang C;Luan G;Ling B;Jia X
鲍曼不动杆菌中氨基糖苷类耐药酶和超广谱β-内酰胺酶的流行已有报道。追踪多药耐药A的风险。鲍曼不动杆菌，本研究旨在确定高水平氨基糖苷类耐药A.鲍曼不动杆菌两年多。118株A.鲍曼不动杆菌在中国成都医学院第一附属医院连续收集。对这些分离株氨基糖苷类耐药的遗传基础进行了研究。结果显示，75株（63.56%）对氨基糖苷类抗生素高度耐药，包括庆大霉素和阿米卡星（最低抑菌浓度≥ 256 μg/ml）。氨基糖苷类耐药基因ant（2
The prevalence of aminoglycoside resistant enzymes has previously been reported and extended-spectrum β-lactamase among Acinetobacter baumannii. To track the risk of multidrug‑resistant A. baumannii, the present study aimed to determine the prevalence of carbapenemases in high‑level aminoglycoside resistant A. baumannii over two years. A total of 118 strains of A. baumannii were consecutively collected in the First Affiliated Hospital of Chengdu Medical College, Chengdu, China. These isolates were investigated on the genetic basis of their resistance to aminoglycosides. The results showed that 75 (63.56%) isolates were high‑level resistant to aminoglycosides, including gentamicin and amikacin (minimum inhibitory concentration,≥ 256 µg/ml). Aminoglycoside‑resistant genes ant (2