Developing optimal search strategies for detecting clinically sound treatment studies in EMBASE.
Developing optimal search strategies for detecting clinically sound treatment studies in EMBASE.
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发表时间：
2006
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通讯作者：
By Sharon S.-L. Wong;N. Wilczynski;B. Haynes
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作者：
By Sharon S.-L. Wong;N. Wilczynski;B. Haynes
在大型书目数据库（如EMBASE）中准确识别治疗相关文章的能力对研究人员和临床医生非常重要。我们的研究旨在开发最佳的搜索策略，以检测2000年在EMBASE中的声音治疗研究。方法将手工检索的期刊与EMBASE检索的候选检索策略进行比较。六名训练有素的研究助理审查了EMBASE中索引的55种期刊，并使用目的和质量指标对文章进行了评级。候选人的搜索策略，识别治疗文章，然后进行测试，检索进行了比较，手搜索数据。计算了策略的操作特性。结果3850篇文章是关于治疗的原创性研究，其中1,256篇（32.6%）是方法学合理的。结合搜索词揭示了一个最佳的执行策略（随机：. tw.或临床试验：. mp。OR值为98.9%，特异性为72.0%。最大化特异性，最佳执行策略（双盲：. mp.或安慰剂：. tw.或盲眼：. tw.）获得了超过96.0%的值，但灵敏度为51.7%。3项策略实现了灵敏度和特异性的最佳优化（随机：或安慰剂：. mp。或双盲：. tw.），这两个值均超过92.0%。结论搜索策略可以在EMBASE中实现高性能的治疗研究检索。
OBJECTIVE The ability to accurately identify articles about therapy in large bibliographic databases such as EMBASE is important for researchers and clinicians. Our study aimed to develop optimal search strategies for detecting sound treatment studies in EMBASE in the year 2000. METHODS Hand searches of journals were compared with retrievals from EMBASE for candidate search strategies. Six trained research assistants reviewed fifty-five journals indexed in EMBASE and rated articles using purpose and quality indicators. Candidate search strategies were developed for identifying treatment articles and then tested, and the retrievals were compared with the hand-search data. The operating characteristics of the strategies were calculated. RESULTS Three thousand eight hundred fifty articles were original studies on treatment, of which 1,256 (32.6%) were methodologically sound. Combining search terms revealed a top performing strategy (random:.tw. OR clinical trial:.mp. OR exp health care quality) with sensitivity of 98.9% and specificity of 72.0%. Maximizing specificity, a top performing strategy (double-blind:.mp. OR placebo:.tw. OR blind: .tw.) achieved a value over 96.0%, but with compromised sensitivity at 51.7%. A 3-term strategy achieved the best optimization of sensitivity and specificity (random:.tw. OR placebo:.mp. OR double-blind:.tw.), with both these values over 92.0%. CONCLUSION Search strategies can achieve high performance for retrieving sound treatment studies in EMBASE.