Infectious diseases: Considerations for the 21st century
Infectious diseases: Considerations for the 21st century
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DOI：
10.1086/319235
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发表时间：
2001-03-01
影响因子：
11.8
通讯作者：
Fauci, AS
中科院分区：
文献类型：
--
作者：
Fauci, AS
21 世纪，无论是发达国家还是发展中国家，传染病学科都将变得更加重要。全球卫生背景下与传染病相关的问题以前所未有的程度被提上世界领导人、卫生政策制定者和慈善机构的议程。这种关注既集中在疫苗开发等科学挑战上，也集中在传染病对经济发展和政治稳定的有害影响上。对全球健康的兴趣导致财政支持水平不断提高，这与最新的技术进步相结合，为 21 世纪的传染病研究提供了非凡的机会。人类和微生物基因组的测序以及功能基因组学的进步将支撑许多领域的重大进展，包括了解人类对疾病的易感性和易感性、微生物发病机制以及开发新的诊断方法、疫苗和疗法。传染病研究将越来越多地与发展中国家所需的医疗基础设施和培训的发展联系起来，以将科学进步转化为实际操作。
The discipline of infectious diseases will assume added prominence in the 21st century in both developed and developing nations. To an unprecedented extent, issues related to infectious diseases in the context of global health are on the agendas of world leaders, health policymakers, and philanthropies. This attention has focused both on scientific challenges such as vaccine development and on the deleterious effects of infectious diseases on economic development and political stability. Interest in global health has led to increasing levels of financial support, which, combined with recent technological advances, provide extraordinary opportunities for infectious disease research in the 21st century. The sequencing of human and microbial genomes and advances in functional genomics will underpin significant progress in many areas, including understanding human predisposition and susceptibility to disease, microbial pathogenesis, and the development new diagnostics, vaccines, and therapies. Increasingly, infectious disease research will be linked to the development of the medical infrastructure and training needed in developing countries to translate scientific advances into operational reality.