Analysis of the clinical effect of olfactory training on olfactory dysfunction after upper respiratory tract infection
Analysis of the clinical effect of olfactory training on olfactory dysfunction after upper respiratory tract infection
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DOI：
10.1080/00016489.2019.1614224
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发表时间：
2019-05-10
影响因子：
1.4
通讯作者：
Zheng, Wei
中科院分区：
文献类型：
--
作者：
Qiao, Xiao-Feng;Wang, Guo-Ping;Zheng, Wei
背景：嗅觉功能障碍是耳鼻咽喉科门诊常见症状。目的：探讨嗅觉训练对上呼吸道感染后嗅觉障碍的临床疗效及其影响因素。材料和方法：本研究共纳入60例URTI所致嗅觉障碍的确诊病例。嗅觉训练持续24周。治疗前、治疗后1个月、3个月、6个月分别进行Sniffin评分卡和阈值辨别识别(TDI)综合评分。结果：发现URTI所致嗅觉障碍患者的气味识别能力下降更为明显。嗅觉训练对嗅觉障碍患者治疗后1、3、6个月的有效率分别为1.67%、26.67%、41.67%。治疗后3个月和6个月的TDI评分显著高于治疗前，但1个月时无显著差异。病程是影响嗅觉训练疗效的显著因素(OR=0.805，95%CI：0.696~0.931)。结论：嗅觉训练能有效治疗URTI所致的嗅觉障碍，尤其能显著提高嗅觉辨别能力和嗅觉辨别能力。意义：为进一步研究嗅觉功能障碍提供有用的数据。
Background: Olfactory dysfunction is a common symptom during otolaryngology outpatient service. Objective: To explore the clinical effect of olfactory training on olfactory dysfunction after upper respiratory tract infection (URTI), and its influence factors. Material and methods: A total of 60 confirmed cases of URTI-induced olfactory dysfunction were enrolled into the present study. The olfactory training lasted for 24 weeks. These patients were tested using Sniffin' Sticks and threshold-discrimination-identification (TDI) composite scoring before treatment, and at 1, 3 and 6 months after treatment. Results: It was found that URTI-induced olfactory dysfunction patients had more evident deterioration in odor identification ability. The effective rates of olfactory training on olfactory dysfunction at 1, 3 and 6 months after treatment were 1.67%, 26.67% and 41.67%, respectively. The TDI scores at the 3rd and 6th months, but not at the 1st month, were significantly higher, when compared to those before treatment. The course of diseases was a significant influence factor on the therapeutic effect of olfactory training (OR = 0.805, 95% CI: 0.696-0.931). Conclusions: Olfactory training can efficiently cure URTI-induced olfactory dysfunction, and in particular, significantly improve the odor discrimination ability and odor identification ability. Significance: Providing useful data for further research regarding olfactory dysfunction.