Single step synthesis, characterization and applications of curcumin functionalized iron oxide magnetic nanoparticles.
Single step synthesis, characterization and applications of curcumin functionalized iron oxide magnetic nanoparticles.
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DOI：
10.1016/j.msec.2016.04.093
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发表时间：
2016-10-01
期刊：
影响因子：
--
通讯作者：
Hilt JZ
中科院分区：
文献类型：
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作者：
Bhandari R;Gupta P;Dziubla T;Hilt JZ
磁性氧化铁纳米粒子在磁共振成像、热疗、靶向给药等领域有着广泛的应用。通过对磁性纳米粒子进行表面修饰，可以获得在生物医学、环境保护、催化等领域具有潜在应用价值的功能化材料。在此，我们报告了一种新的和多功能的一步开发姜黄素功能化的磁性Fe3O4纳米粒子的方法，没有任何额外的连接器，使用一个简单的共沉淀技术。采用透射电子显微镜、X射线衍射、傅立叶变换红外光谱和热重分析对磁性纳米粒子进行了表征。开发的MNP用于细胞应用中，用于保护免受炎症剂，多氯联苯（PCB）分子的影响。用于细胞活力应用的新型单步姜黄素涂覆的磁性Fe3O4纳米颗粒，没有任何额外的连接体
Magnetic iron oxide nanoparticles have been well known for their applications in magnetic resonance imaging (MRI), hyperthermia, targeted drug delivery, etc. The surface modification of these magnetic nanoparticles has been explored extensively to achieve functionalized materials with potential application in biomedical, environmental and catalysis field. Herein, we report a novel and versatile single step methodology for developing curcumin functionalized magnetic Fe3O4 nanoparticles without any additional linkers, using a simple coprecipitation technique. The magnetic nanoparticles (MNPs) were characterized using transmission electron microscopy, x-ray diffraction, fourier transform infrared spectroscopy and thermogravimetric analysis. The developed MNPs were employed in a cellular application for protection against an inflammatory agent, a polychlorinated biphenyl (PCB) molecule. Novel single step curcumin coated magnetic Fe3O4 nanoparticles without any additional linkers for cell viability applications