Protein intake, uric acid metabolism and protein efficiency ratio in growing chicks.
Protein intake, uric acid metabolism and protein efficiency ratio in growing chicks.
复制标题
生长中雏鸡的蛋白质摄入量、尿酸代谢和蛋白质效率。
DOI：
10.1093/jn/107.6.959
复制
发表时间：
1977
期刊：
影响因子：
--
通讯作者：
A. Clifford
中科院分区：
文献类型：
--
作者：
P. Hevia;A. Clifford
日粮蛋白质摄入量的改变引起的雏鸡尿酸代谢的变化与日粮蛋白质质量有关。测定了日粮蛋白质含量为11%、20%、43%和80%的生长期雏鸡血浆尿酸水平、总尿酸排泄量和蛋白质效率。二次多项式的决定系数为93%，最好的描述膳食蛋白质摄入量和总尿酸输出之间的关系。二次多项式的决定系数为58%，最好的描述蛋白质摄入量和膳食蛋白质质量之间的关系，所测量的蛋白质效率比方法。血浆尿酸水平与膳食蛋白质摄入量呈线性正相关，决定系数为42%。整合这些关系与嘌呤的生物合成和再利用，将提高我们的知识控制尿酸生产的鸡，并可能在人类痛风。这些数据表明，总尿酸排泄量和排泄物中尿酸浓度可能是测定鸡饲粮蛋白质质量的非常有用的方法。数据还表明，膳食蛋白质水平显着影响尿酸的产生。
Changes in uric acid metabolism in chicks resulting from alterations in dietary protein intake have been correlated with dietary protein quality. Plasma uric acid levels, total uric acid excretion and protein efficiency ratio were measured in growing chicks fed diets containing 11%, 20%, 43% and 80% protein. A second degree polynomial with a coefficient of determination of 93% best described the relationship between dietary protein intake and total uric acid output. A second degree polynomial with a coefficient of determination of 58% best described the relationship between protein intake and dietary protein quality as measured by the protein efficiency ratio method. Plasma uric acid level was correlated, positively and linearly, with dietary protein intake and had a coefficient of determination of 42%. An integration of these relationships with purine biosynthesis and reutilization would enhance our knowledge of the control of uric acid production in the chick and possibly in human gout. The data demonstrate that total uric acid excretion and uric acid concentration in excreta may represent very useful methods of measuring dietary protein quality in the chick. The data also demonstrate that dietary protein level markedly affects uric acid production.