Homozygous protein C deficiency in a newborn. Clinicopathologic correlation.
Homozygous protein C deficiency in a newborn. Clinicopathologic correlation.
复制标题
新生儿纯合蛋白 C 缺乏症。
DOI：
10.1001/archneur.1988.00520260102029
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发表时间：
1988
影响因子：
--
通讯作者：
J. Gregorios
中科院分区：
文献类型：
--
作者：
S. Tarras;C. Gadia;L. Meister;E. Roldan;J. Gregorios
A rare case of homozygous protein C deficiency occurred in a newborn. The patient presented with purpura fulminans in the first few hours after birth and showed multiple hemorrhagic lesions on computed tomography of the brain at 5 days of age. Neurologic symptoms developed at two weeks and the patient died at 37 weeks. His protein C level was less than 5%. Autopsy revealed thrombosis of the dural sinuses, multiple cortical infarcts, intraparenchymal hemorrhages, and hydrocephalus. The pathologic findings are correlated with the neurologic deficits and previously documented cases are reviewed.
严重的纯合蛋白 C 缺乏症。
DOI：
10.1016/s0022-3476(84)80013-x
发表时间：
1984
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Sills,RH;Marlar,RA;Montgomery,RR;Deshpande,GN;Humbert,JR
通讯作者：
Humbert,JR