Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography Datasets: The Next Frontier in Noninvasive Assessment of Coronary Artery Disease.
Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography Datasets: The Next Frontier in Noninvasive Assessment of Coronary Artery Disease.
复制标题
DOI：
10.1155/2018/2680430
复制
发表时间：
2018
影响因子：
--
通讯作者：
Rabbat M
中科院分区：
文献类型：
--
作者：
Ball C;Pontone G;Rabbat M
来自冠状动脉CTA数据集（FFRCT）的血流储备分数（FFR）是心血管成像的一项重大进步，可为心脏团队提供关键信息，而不会使患者面临过度风险。此前，已证明在心导管插入术期间获得的侵入性FFR测量值可减少造影剂使用、支架数量和护理成本，并改善结局。然而，在心导管室中常规使用FFR存在障碍。使用静息3D冠状动脉CTA图像（使用计算流体动力学）获得FFRCT值。多项多中心临床试验已证明FFRCT在诊断功能显著性冠状动脉疾病方面优于传统冠状动脉CTA。该综述提供了FFR的背景、FFRCT的技术方面、临床应用和FFRCT值的解释、临床试验数据以及该技术的未来发展方向。
Fractional flow reserve (FFR) derived from coronary CTA datasets (FFRCT) is a major advance in cardiovascular imaging that provides critical information to the Heart Team without exposing the patient to excessive risk. Previously, invasive FFR measurements obtained during a cardiac catheterization have been demonstrated to reduce contrast use, number of stents, and cost of care and improve outcomes. However, there are barriers to routine use of FFR in the cardiac catheterization suite. FFRCT values are obtained using resting 3D coronary CTA images using computational fluid dynamics. Several multicenter clinical trials have demonstrated the diagnostic superiority of FFRCT over traditional coronary CTA for the diagnosis of functionally significant coronary artery disease. This review provides a background of FFR, technical aspects of FFRCT, clinical applications and interpretation of FFRCT values, clinical trial data, and future directions of the technology.
登录
查看更多内容
影响因子：
5.4
作者：
Kitabata, Hironori;Leipsic, Jonathon;Akasaka, Takashi
通讯作者：
Akasaka, Takashi
影响因子：
24
作者：
Hlatky, Mark A.;De Bruyne, Bernard;Douglas, Pamela S.
通讯作者：
Douglas, Pamela S.
影响因子：
37.8
作者：
De Bruyne, B;Hersbach, F;Wijns, W
通讯作者：
Wijns, W
影响因子：
39.3
作者：
Douglas PS;Pontone G;Hlatky MA;Patel MR;Norgaard BL;Byrne RA;Curzen N;Purcell I;Gutberlet M;Rioufol G;Hink U;Schuchlenz HW;Feuchtner G;Gilard M;Andreini D;Jensen JM;Hadamitzky M;Chiswell K;Cyr D;Wilk A;Wang F;Rogers C;De Bruyne B;PLATFORM Investigators
通讯作者：
PLATFORM Investigators
DOI：
10.1093/ehjci/jex068
发表时间：
2018-04-01
期刊：
European heart journal. Cardiovascular Imaging
影响因子：
--
作者：
Jensen JM;Bøtker HE;Mathiassen ON;Grove EL;Øvrehus KA;Pedersen KB;Terkelsen CJ;Christiansen EH;Maeng M;Leipsic J;Kaltoft A;Jakobsen L;Sørensen JT;Thim T;Kristensen SD;Krusell LR;Nørgaard BL
通讯作者：
Nørgaard BL