MEASURING ESOPHAGEAL MOTILITY WITH A NEW INTRALUMINAL IMPEDANCE DEVICE - FIRST CLINICAL-RESULTS IN REFLUX PATIENTS
MEASURING ESOPHAGEAL MOTILITY WITH A NEW INTRALUMINAL IMPEDANCE DEVICE - FIRST CLINICAL-RESULTS IN REFLUX PATIENTS
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DOI：
10.3109/00365529409092496
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发表时间：
1994-08-01
影响因子：
1.9
通讯作者：
RAU, G
中科院分区：
文献类型：
--
作者：
FASS, J;SILNY, J;RAU, G
背景资料：本研究旨在探讨食管腔内阻抗测量对反流患者食管动力障碍诊断的有效性。研究方法：在一项前瞻性研究中，10名志愿者和10名II-III级反流性食管炎患者使用一种新的阻抗装置检测食管动力模式。灌注测压与阻抗描记相关。测试膳食是具有液体至半固体粘度的三种不同制剂中的盐水和凝乳。结果：随着胶团粘度的增加，食管转运明显延迟（P < 0.01）。在反流患者中，在发炎的食管区域中观察到了显著（p < 0.001）的团输运延迟。在反流患者中，通过阻抗程序检测到下食管和下食管括约肌的收缩力降低，表明反流性食管炎的病理动力模式最有可能继发于组织炎症。结论：我们的结论是，阻抗程序可以提供额外的重要信息团运输和食管壁运动。
Background: The study was undertaken to determine the validity of intraluminal impedance measuring for the diagnosis of esophageal motility disorders in reflux patients. Methods: A new impedance device was used for the detection of esophageal motility patterns in a prospective study with 10 volunteers and 10 patients with reflux esophagitis grade II-III. Perfused manometry was correlated with the impedance tracings. Test meals were saline and curd in three different preparations with liquid to semisolid viscosity. Results: There was a marked delay in esophageal transport with increasing viscosity of the bolus (p < 0.01). A significant (p < 0.001) delay of the bolus transport in the inflamed esophageal areas was seen in reflux patients. A reduced contractility of the lower esophagus and the lower esophageal sphincter was detected by the impedance procedure in reflux patients, indicating that the pathologic motility patterns in reflux esophagitis are most likely secondary to the tissue inflammation. Conclusion: We conclude that impedance procedures may give additional significant information about bolus transport and esophageal wall movements.