EFFECT OF PRIOR MYOCARDIAL-INFARCTION AND EXTENT AND LOCATION OF CORONARY-DISEASE ON ACCURACY OF EXERCISE ECHOCARDIOGRAPHY

EFFECT OF PRIOR MYOCARDIAL-INFARCTION AND EXTENT AND LOCATION OF CORONARY-DISEASE ON ACCURACY OF EXERCISE ECHOCARDIOGRAPHY
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DOI:
10.1016/s0735-1097(87)80195-x
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发表时间:
1987-09-01
影响因子:
24
通讯作者:
FEIGENBAUM, H
FEIGENBAUM, H
中科院分区:
医学1区
文献类型:
--
作者:
ARMSTRONG, WF;ODONNELL, J;FEIGENBAUM, H

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运动超声心动图是一种用于评估可疑冠心病患者的新兴技术。在这项研究中,对123例患者进行了静息和运动后即刻超声心动图检查,这些患者根据既往心肌梗死史和心导管术时冠状动脉狭窄的数量和位置进行分层。静息和运动后研究中室壁运动异常的位置与冠状动脉狭窄的位置相关。运动超声心动图检测多支病变患者冠状动脉病变的敏感性为97%,无心肌梗死史者为86%。对单支病变的敏感度分别为100%和72%。59例患者存在多支血管病变,但只有32例(54%)被明确诊断为多支病变。12例冠状动脉病变患者静息和运动超声心动图正常,其中8例为单支病变。结论:运动超声心动图的主观分析能准确地诊断出大多数冠心病患者。它对多支冠状动脉疾病的敏感度最高。它仅限于单支冠脉疾病患者和准确识别多支冠脉疾病患者的亚组。
Exercise echocardiography is an emerging technique for the evaluation of patients with suspected coronary artery disease. In this study, rest and immediate postexercise echocardiograms were performed in 123 patients who were stratified on the basis of prior myocardial infarction and the number and location of coronary artery stenoses at cardiac catheterization. The location of wall motion abnormalities on rest and postexercise studies was correlated with the location of coronary artery stenoses. The sensitivity of exercise echocardiography for detecting coronary artery disease in patients with multivessel disease was 97% in those with and 86% in those without prior infarction. The coresponding sensitivity for patients with single vessel disease was 100% and 72%, respectively. Multivessel disease was present in 59 patients, but specifically identified as such in only 32 (54%). Normal rest and exercise echocardiograms were seen in 12 patients with coronary artery dosease, 8 of whom had single vessel disease. It is concluded that the subjective analysis of the exercise echocardiogram accurately identifies the majority of patients with coronary artery disease. Its sensitivity is greatest in those with multivessel coronary disease. It is limited in those with single vessel coronary disease and in accurately identifying the subset of patients with multivessel disease.