B(C6F5)3: a robust catalyst for the activation of CO2 and dimethylamine borane for the N-formylation reactions
B(C6F5)3: a robust catalyst for the activation of CO2 and dimethylamine borane for the N-formylation reactions
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B（C6 F5）3：一种用于活化CO2和二甲胺硼烷用于N-Cl 2反应的稳健催化剂
DOI：
10.1039/c8nj02816h
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发表时间：
2018-09
影响因子：
3.3
通讯作者：
Vitthal B. Saptal;G. Juneja;B. Bhanage
中科院分区：
文献类型：
--
作者：
Vitthal B. Saptal;G. Juneja;B. Bhanage
In this work, B(C6F5)3 is utilized as an organocatalyst for the transition-metal-free N-formylation of amines using carbon dioxide (CO2) as a C1 source and dimethylamine borane (Me2NH·BH3) as a green hydrogen transfer source at 80 °C. Most reported works utilize silane and hydrogen for the N-formylation reactions using CO2 which have thus far been limited by low atom economy, high cost or the use of harsh reaction conditions. This catalytic protocol affords a broad range of formylated products in moderate to excellent yields under mild reaction conditions with a high TON and TOF. The bulky boron (B(C6F5)3) catalyst reacts with amines and forms a Frustrated Lewis Pair (FLP) and activates CO2 and Me2NH·BH3 molecules. Additionally, this boron catalyst shows high catalytic activity for the cyclization of o-phenylenediamines using CO2 and Me2NH·BH3 to synthesize benzimidazoles.
