Mild and novel electrochemical preparation of β-cyclodextrin/graphene nanocomposite film for super-sensitive sensing of quercetin
Mild and novel electrochemical preparation of β-cyclodextrin/graphene nanocomposite film for super-sensitive sensing of quercetin
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DOI：
10.1016/j.bios.2014.02.014
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发表时间：
2014-07-15
影响因子：
12.6
通讯作者：
Jiang, Lin
中科院分区：
文献类型：
--
作者：
Zhang, Zhen;Gu, Shuqing;Jiang, Lin
开发了一种基于电化学技术的温和新颖的制备策略，用于制造电沉积石墨烯（E-GR）和聚合β-环糊精（P-β cD）纳米复合薄膜。通过扫描电子显微镜（SEM）、透射电子显微镜（TEM）和拉曼光谱研究了GR基纳米复合材料的结构和形貌。同时，通过循环伏安法（CV）和微分脉冲伏安法（DPV）对这种纳米复合材料的电化学性能进行了表征。基于E-GR和P-β CD的协同作用，成功制备了槲皮素的超灵敏电化学传感器。在最佳条件下，槲皮素的测定范围为0.005～20 μM，检出限低至0.001 μM（S/N=3）。此外，该传感器还表现出优异的灵敏度、良好的再现性和稳定性。为了进一步研究该传感器的实际适用性，对实际样品进行了测定，得到了满意的结果。 (c) 2014 Elsevier B.V. 保留所有权利。
A mild and novel preparation tactics based on electrochemical techniques for the fabrication of electro-deposited graphene (E-GR) and polymerized beta-cyclodextrin (P-beta cD) nanocomposite film were developed. The structure and morphology of GR-based nanocomposite were investigated by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Raman spectroscopy. Simultaneously, the electrochemical properties of this nanocomposite were characterized by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Based on the synergistic effect of E-GR and P-beta CD, a super-sensitive electrochemical sensor for quercetin was successfully fabricated. Under optimum conditions, the determination range for quercetin was from 0.005 to 20 mu M with a low detection limit of 0.001 mu M (S/N=3). Moreover, this sensor also displays excellent sensitivity, fine reproducibility and stability. To further study the practical applicability of the proposed sensor, the determination of real samples was carried out with satisfactory results. (c) 2014 Elsevier B.V. All rights reserved.