DomainDraw: A Macromolecular Feature Drawing Program
DomainDraw: A Macromolecular Feature Drawing Program
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DomainDraw：高分子特征绘图程序
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
N. Hamilton
中科院分区：
文献类型：
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作者：
J. Fink;N. Hamilton
可视化生物大分子的功能和结构特征是交流和分析生物数据的一个重要方面，例如与核苷酸结合位点相关的跨膜结构域的存在或启动子中转录因子结合位点的组织。然而，这并不一定是一项微不足道的任务，特别是当特征信息复杂或冗长时。虽然有一些可用的工具可以创建这些图像，但是还没有实现用于自动生成用于显示特性信息的表示质量图形的特定目的。我们已经实现了DomainDraw，这是一个可视化工具，可以用来生成生物大分子的示意图，以表示用户指定的域或基元的相对位置和范围。用户指定感兴趣的域的名称、位置和范围，DomainDraw根据这些参数生成图像。可选参数包括区域颜色和形状、图像大小以及是否使用特定区域对齐多个蛋白质。DomainDraw是一个公开的web服务器，可以访问http://domaindraw.imb.uq.edu.au。可执行文件可通过联系作者获得。
Visualization of functional and structural features of biological macromolecules is an important aspect of communicating and analyzing biological data, for example the presence of a transmembrane domain in relation to a nucleotide binding site or the organization of transcription factor binding sites in a promoter. However, this is not necessarily a trivial task especially when the feature information is complex or lengthy. While there are some tools available that can create these images, none have been implemented for the specific purpose of automating the generation of presentation-quality graphics for displaying feature information. We have implemented DomainDraw, a visualization tool that can be used to generate schematic diagrams of biological macromolecules for the purpose of representing the relative position and range of user-specified domains or motifs. The user specifies the name, position, and range of the domains of interest and DomainDraw generates the image based on these parameters. Optional parameters include domain color and shape, image size, and whether to align multiple proteins using a particular domain. DomainDraw is publicly available as a web server and can be accessed at http://domaindraw.imb.uq.edu.au. The executable may be obtained by contacting the authors.