Anchoring local translation in neurons.
Anchoring local translation in neurons.
复制标题
将局部翻译锚定在神经元中。
DOI:
10.1016/j.cell.2010.04.031
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发表时间:
2010
期刊:
影响因子:
64.5
通讯作者:
Martin,KelseyC
中科院分区:
文献类型:
--
作者:
Martin,KelseyC
In probing how protein synthesis in neurons is coupled to extracellular stimuli, Tcherkezian et al. (2010) discover that the receptor protein DCC anchors components of the translation machinery at the plasma membrane. Binding of DCC to its ligand, netrin, triggers the release of these components to initiate spatially restricted protein synthesis.