Effect of prebiotic supplementation and calcium intake on body mass index
Effect of prebiotic supplementation and calcium intake on body mass index
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DOI：
10.1016/j.jpeds.2007.03.043
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发表时间：
2007-09-01
影响因子：
5.1
通讯作者：
Ellis, Kenneth J.
中科院分区：
文献类型：
--
作者：
Abrams, Steven A.;Griffin, Ian J.;Ellis, Kenneth J.
目的评价益生元补充剂和常规钙摄入量对青春期生长期间身体组成变化的影响。研究设计我们用双能X射线吸收法测量了97名年轻青少年的人体测量学和体脂，他们被随机分配到每天服用益生元补充剂或麦芽糊精（对照）1年。结果服用益生元补充剂的受试者体重指数增加较小（BMI）与对照组相比（BMI差异0.52 +/- 0.16 kg/m2，P = 0.016），BMI Z评分（差异0.13 +/- 0.06，P = 0.048）和总脂肪量（差异0.84 +/- 0.36 kg，P = 0.022）。益生元组维持其基线BMI Z评分（0.03 +/- 0.01，配对t检验，P = .30），尽管对照组的BMI Z评分显著增加（0.13 ± 0.03，P < .001）。考虑到钙摄入量>= 700 mg/d的受试者，接受益生元补充剂的受试者的BMI相对变化比对照组受试者低0.82 kg/m2（P <0.01），BMI Z评分比对照组受试者低0.20（P = 0.003）。结论补充益生元和避免低钙摄入对调节青春期BMI和其他身体成分变化有显著作用。
Objective To assess the effects of a prebiotic supplement and usual calcium intake on body composition changes during pubertal growth.Study design We measured anthropometry and body fat with dual-energy X-ray absorptiometry in 97 young adolescents who were randomized to receive either a daily prebiotic supplement or maltodextrin (control) for 1 year.Results Subjects who received the prebiotic supplement had a smaller increase in body mass index (BMI) compared with the control group (BMI difference 0.52 +/- 0.16 kg/m(2), P = .016), BMI Z-score (difference 0.13 +/- 0.06, P = .048) and total fat mass (difference 0.84 +/- 0.36 kg, P =.022). The prebiotic group maintained their baseline BMI Z-score (0.03 +/- 0.01, paired t test, P = .30), although BMI Z-score increased significantly in the control group (0.13 0.03, P < .001). In considering subjects whose usual calcium intake was >= 700 mg/d, those who received the prebiotic supplement had a relative change in BMI that was 0.82 kg/m(2) less than control subjects (P < .01), and BMI Z-score that was 0.20 less than control subjects (P = .003). Differences tended to be maintained 1 year after supplementation was stopped.Conclusion Prebiotic supplementation and avoidance of a low calcium intake can have significant effects in modulating BMI and other body composition changes during puberty.