An increase in the negative surface charge of U937 cells exposed to a pulsed magnetic field.
An increase in the negative surface charge of U937 cells exposed to a pulsed magnetic field.
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暴露于脉冲磁场的 U937 细胞表面负电荷增加。
DOI：
10.1002/bem.2250120307
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发表时间：
1991
影响因子：
1.9
通讯作者：
Tipnis,P
中科院分区：
文献类型：
--
作者：
Smith,OM;Goodman,EM;Greenebaum,B;Tipnis,P
脉冲磁场已被用于促进骨折的愈合，并据称用于软组织损伤的愈合。然而，对其作用机制知之甚少。我们报告了非贴壁哺乳动物细胞系U937的质膜变化，该细胞系暴露于25-pps磁场48小时。水相聚合物两相分配研究表明，磁场暴露的细胞表现出增加的负表面电荷，但膜疏水性没有显着改变。所观察到的暴露细胞的膜电负性增加并不反映生长速率的显著变化。
Pulsed magnetic fields have been used to enhance healing of bone fractures and purportedly of lesions in soft tissue. However, their mechanism of action is poorly understood. We report changes in the plasma membrane of a nonadherent mammalian cell line, U937, which was exposed to a 25‐pps magnetic field for 48 hours. Aqueous polymer two‐phase partition studies showed that magnetic‐field‐exposed cells exhibited an increased negative surface charge but membrane hydrophobicity was not significantly altered. The observed increase in membrane electronegativity of exposed cells did not reflect a significant change in growth rate.